EPM2A antibody (N-Term)
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- Target See all EPM2A Antibodies
- EPM2A (Epilepsy, Progressive Myoclonus Type 2A, Lafora Disease (Laforin) (EPM2A))
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Binding Specificity
- N-Term
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Reactivity
- Human, Rat, Cow, Dog, Pig, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This EPM2A antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- ALALQEPGLW LGEVELAAEE AAQDGAEPGR VDTFWYKFLK REPGGELSWE
- Predicted Reactivity
- Cow: 100%, Dog: 90%, Human: 100%, Pig: 100%, Rabbit: 100%, Rat: 86%
- Characteristics
- This is a rabbit polyclonal antibody against EPM2A. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product EPM2A Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 317 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- EPM2A (Epilepsy, Progressive Myoclonus Type 2A, Lafora Disease (Laforin) (EPM2A))
- Alternative Name
- EPM2A (EPM2A Products)
- Synonyms
- TG-B antibody, Tg(TcraK,TcrbK)TG-BFlv antibody, EPM2 antibody, MELF antibody, laforin antibody, EPM2A, laforin glucan phosphatase antibody, epilepsy, progressive myoclonic epilepsy, type 2 gene alpha antibody, EPM2A antibody, Epm2a antibody
- Background
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This gene encodes a dual-specificity phosphatase that associates with polyribosomes. The encoded protein may be involved in the regulation of glycogen metabolism. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. Alternative splicing results in multiple transcript variants.
Alias Symbols: EPM2, MELF
Protein Interaction Partner: NHLRC1, EPM2A, PPP1R3D, PRKAA1, STUB1, PRKAB2, PRKAA2, PPP1R3C, UBC, GSK3B, NFU1, EPM2AIP1, UBE2D1, HSPA5,
Protein Size: 317 - Molecular Weight
- 35 kDa
- Gene ID
- 7957
- NCBI Accession
- NM_001018041, NP_001018051
- Pathways
- Cellular Glucan Metabolic Process
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