MCPH1 antibody (C-Term)
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- Target See all MCPH1 Antibodies
- MCPH1 (Microcephalin 1 (MCPH1))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MCPH1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- VLDDSCDGFK DLIKPHEELK KSGRGKKPTR TLVMTSMPSE KQNVVIQVVD
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against MCPH1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product MCPH1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 835 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- MCPH1 (Microcephalin 1 (MCPH1))
- Alternative Name
- MCPH1 (MCPH1 Products)
- Synonyms
- RGD1560642 antibody, MGC83773 antibody, MCPH1 antibody, mct antibody, brit1 antibody, MGC148665 antibody, BRIT1 antibody, MCT antibody, 5430437K10Rik antibody, D030046N04Rik antibody, microcephalin 1 antibody, microcephalin 1 S homeolog antibody, microcephaly, primary autosomal recessive 1 antibody, Mcph1 antibody, mcph1.S antibody, MCPH1 antibody, mcph1 antibody
- Background
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This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome.
Alias Symbols: BRIT1, FLJ12847, MCT
Protein Interaction Partner: KDM1A, PHF11, TADA2A, ABCC2, E2F1, CDC27, CHD4, H2AFX, CHEK1, MDC1, TP53BP1, SMARCC2, SMARCC1, SMARCB1, SMARCA4, SMARCA2, RAD51, NBN, MCM2, BRCA2, ATR, ATM, RPA1,
Protein Size: 835 - Molecular Weight
- 93 kDa
- Gene ID
- 79648
- NCBI Accession
- NM_024596, NP_078872
- UniProt
- Q8NEM0
- Pathways
- Stem Cell Maintenance
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