PSTPIP1 antibody (N-Term)
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- Target See all PSTPIP1 Antibodies
- PSTPIP1 (Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Zebrafish (Danio rerio), Pig, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PSTPIP1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- HIQLALTLRE ELRSLEEFRE RQKEQRKKYE AVMDRVQKSK LSLYKKAMES
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 79%, Rat: 100%, Zebrafish: 92%
- Characteristics
- This is a rabbit polyclonal antibody against PSTPIP1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product PSTPIP1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 416 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PSTPIP1 (Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1))
- Alternative Name
- PSTPIP1 (PSTPIP1 Products)
- Synonyms
- cd2bp1 antibody, cd2bp1l antibody, cd2bp1s antibody, h-pip antibody, papas antibody, pstpip antibody, PSTPIP1 antibody, CD2BP1 antibody, CD2BP1L antibody, CD2BP1S antibody, H-PIP antibody, PAPAS antibody, PSTPIP antibody, def-2 antibody, proline-serine-threonine phosphatase interacting protein 1 antibody, proline-serine-threonine phosphatase interacting protein 1 S homeolog antibody, proline-serine-threonine phosphatase-interacting protein 1 antibody, PSTPIP1 antibody, pstpip1.S antibody, pstpip1 antibody, Pstpip1 antibody
- Background
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The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome.
Alias Symbols: CD2BP1, CD2BP1L, CD2BP1S, H-PIP, PAPAS, PSTPIP
Protein Interaction Partner: RTP5, TRAF3IP3, FBXL18, SH2D4A, PCDHB14, UBE2W, FAM90A1, PRPF31, LSM4, BUB3, ZNF175, TULP3, SPG7, SDCBP, MVP, WASL, DNM2, MED28, SHBG, KHDRBS1, WAS, TUBB, WIPF1, HSPA1A, CARS, ACTB, PTPN18, WASF2, WASF1, CD2AP, PTPN12, MEFV, ABL1, CD2, FASLG, BZW2, RPL36,
Protein Size: 416 - Molecular Weight
- 47 kDa
- Gene ID
- 9051
- NCBI Accession
- NM_003978, NP_003969
- UniProt
- O43586
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