GLIPR1 antibody (Middle Region)

Catalog No. ABIN2789910

Product Details anti-GLIPR1 Antibody

Target: GLIPR1 (GLI Pathogenesis-Related 1 (GLIPR1))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLIPR1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SLGENIWTGS VPIFSVSSAI TNWYDEIQDY DFKTRICKKV CGHYTQVVWA

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against GLIPR1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human GLIPR1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 266 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GLIPR1

Target: GLIPR1 (GLI Pathogenesis-Related 1 (GLIPR1))

Alternative Name: GLIPR1 (GLIPR1 Products)

Synonyms: CRISP7 antibody, GLIPR antibody, RTVP1 antibody, 2410114O14Rik antibody, RTVP-1 antibody, mRTVP-1 antibody, GLIPR1 antibody, zgc:65887 antibody, GLI pathogenesis related 1 antibody, GLI pathogenesis-related 1 antibody, GLI pathogenesis-related 1 (glioma) antibody, GLI pathogenesis-related 1b antibody, GLIPR1 antibody, Glipr1 antibody, glipr1b antibody

Background: This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized.
Alias Symbols: CRISP7, GLIPR, RTVP1
Protein Interaction Partner: UBC,
Protein Size: 266

Molecular Weight: 28 kDa

Gene ID: 11010

NCBI Accession: NM_006851, NP_006842

UniProt: P48060

Pathways: Regulation of Lipid Metabolism by PPARalpha