GLIPR1 antibody (AA 22-140)

Catalog No. ABIN7267387

Product Details anti-GLIPR1 Antibody

Target: GLIPR1 (GLI Pathogenesis-Related 1 (GLIPR1))

Binding Specificity: AA 22-140

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLIPR1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: GLIPR1 Rabbit pAb

Sequence: ANILPDIENE DFIKDCVRIH NKFRSEVKPT ASDMLYMTWD PALAQIAKAW ASNCQFSHNT RLKPPHKLHP NFTSLGENIW TGSVPIFSVS SAITNWYDEI QDYDFKTRIC KKVCGHYTQ

Cross-Reactivity: Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 22-140 of human GLIPR1 (NP_006842.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GLIPR1

Target: GLIPR1 (GLI Pathogenesis-Related 1 (GLIPR1))

Alternative Name: GLIPR1 (GLIPR1 Products)

Synonyms: CRISP7 antibody, GLIPR antibody, RTVP1 antibody, 2410114O14Rik antibody, RTVP-1 antibody, mRTVP-1 antibody, GLIPR1 antibody, zgc:65887 antibody, GLI pathogenesis related 1 antibody, GLI pathogenesis-related 1 antibody, GLI pathogenesis-related 1 (glioma) antibody, GLI pathogenesis-related 1b antibody, GLIPR1 antibody, Glipr1 antibody, glipr1b antibody

Background: This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized.,GLIPR1,CRISP7,GLIPR,RTVP1,Cancer,Tumor suppressors,p53 pathway,Invasion and Metastasis,Cell Biology & Developmental Biology,Apoptosis,GLIPR1

Molecular Weight: 26kDa/30kDa

Gene ID: 11010

UniProt: P48060

Pathways: Regulation of Lipid Metabolism by PPARalpha