MRPL2 antibody (N-Term)

Catalog No. ABIN2791668

Product Details anti-MRPL2 Antibody

Target: MRPL2 (Mitochondrial Ribosomal Protein L2 (MRPL2))

Binding Specificity: N-Term

Reactivity: Human, Cow, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GGGHKQRYRM IDFLRFRPEE TKSGPFEEKV IQVRYDPCRS ADIALVAGGS

Predicted Reactivity: Cow: 80%, Dog: 87%, Horse: 93%, Human: 100%, Pig: 80%, Rabbit: 80%

Characteristics: This is a rabbit polyclonal antibody against MRPL2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human MRPL2

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRPL2

Target: MRPL2 (Mitochondrial Ribosomal Protein L2 (MRPL2))

Alternative Name: MRPL2 (MRPL2 Products)

Synonyms: MRP-L14 antibody, RPML14 antibody, CGI-22 antibody, Rpml14 antibody, mitochondrial ribosomal protein L2 antibody, MRPL2 antibody, Mrpl2 antibody

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL2 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 12q.
Alias Symbols: MRP-L14, RPML14
Protein Interaction Partner: GRSF1, CMTM4, MRPL24, MRPL9, MRPL11, MRPL40, MRPL14, DDX28, MRPL16, MRPL37, MRPL4, MRPL13, FUBP1, EIF3C, TUFM, RPS18, RPS15, MRPL23, SLC25A3, CUL3, UBC, ICT1,
Protein Size: 305

Molecular Weight: 33 kDa

Gene ID: 51069

NCBI Accession: NM_015950, NP_057034

UniProt: Q5T653