MAD2L1 antibody (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast)) (Middle Region)

Details for Product anti-MAD2L1 Antibody No. ABIN2792179, Supplier: Log in to see
Antigen
  • cb408
  • zgc:112133
  • MAD2L1
  • mad2
  • XMad2
  • AA673185
  • MAD2
  • HSMAD2
  • MAD2 mitotic arrest deficient-like 1 (yeast)
  • MAD2 mitotic arrest deficient-like 1
  • MAD2L1
  • mad2l1
  • LOC100218172
  • Mad2l1
Epitope
Middle Region
19
8
7
6
4
4
4
3
3
2
2
2
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Mouse (Murine), Rat (Rattus)
121
35
32
8
6
4
4
4
3
3
3
2
2
1
Host
Rabbit
71
34
15
1
Clonality
Polyclonal
Conjugate
This MAD2L1 antibody is un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
102
46
23
22
21
20
13
6
2
1
1
1
1
1
Options
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Immunogen The immunogen is a synthetic peptide directed towards the middle region of human MAD2L1
Sequence MKCQSYCEPP SYRPMHHEDF KEDLKKFRTK SRTWAGEKSK REMYSRLKKL
Predicted Reactivity Cow: 100%, Dog: 100%, Guinea Pig: 100%, Mouse: 100%, Rat: 100%
Characteristics This is a rabbit polyclonal antibody against MAD2L1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name MAD2L1 (MAD2L1 Antibody Abstract)
Background MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate.MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HSMAD2, MAD2
Protein Interaction Partner: ANAPC2, KEAP1, MAD2L1BP, SDCBP, CDC27, BUB1B, TSC22D4, TRIP13, MAD1L1, CDC20, BAG5, UBC, RNF2, OXSR1, RABAC1, ZW10, TP73, MAD2L1, ANAPC4, DAXX, APP, BUB3, CUL3, HSF1, CUEDC2, UBD, NSL1, Gm9174, Cdc16, Cdc23, UBE2C, KLHL13, MAD2L2, NDC80, ADAM17, ESR2, MBL
Protein Size: 205
Molecular Weight 23 kDa
Gene ID 4085
NCBI Accession NM_002358, NP_002349
UniProt Q13257
Research Area Cell Cycle
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 205 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-MAD2L1 antibody (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast)) (Middle Region) (ABIN2792179) WB Suggested Anti-MAD2L1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Background publications Hisaoka, Matsuyama, Hashimoto: "Aberrant MAD2 expression in soft-tissue sarcoma." in: Pathology international, Vol. 58, Issue 6, pp. 329-33, 2008 (PubMed).