F2RL3
Reactivity: Human
WB, ELISA, IF
Host: Rabbit
Polyclonal
unconjugated
Application Notes
IF: 1:100. WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative
Sodium azide
Precaution of Use
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Storage
4 °C,-20 °C
Kahn, Nakanishi-Matsui, Shapiro, Ishihara, Coughlin: "Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin." in: The Journal of clinical investigation, Vol. 103, Issue 6, pp. 879-87, (1999) (PubMed).
Kahn, Hammes, Botka, Coughlin: "Gene and locus structure and chromosomal localization of the protease-activated receptor gene family." in: The Journal of biological chemistry, Vol. 273, Issue 36, pp. 23290-6, (1998) (PubMed).
Xu, Andersen, Whitmore, Presnell, Yee, Ching, Gilbert, Davie, Foster: "Cloning and characterization of human protease-activated receptor 4." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 12, pp. 6642-6, (1998) (PubMed).
Kahn, Zheng, Huang, Bigornia, Zeng, Moff, Farese, Tam, Coughlin: "A dual thrombin receptor system for platelet activation." in: Nature, Vol. 394, Issue 6694, pp. 690-4, (1998) (PubMed).
Target
F2RL3
(Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3))