Complement Factor B antibody (AA 26-751) (HRP)

Catalog No. ABIN2836419

Product Details anti-Complement Factor B Antibody (HRP)

Target: Complement Factor B (CFB)

Binding Specificity: AA 26-751

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Complement Factor B antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Complement factor B protein (26-751AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze.
Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Complement Factor B

Target: Complement Factor B (CFB)

Alternative Name: CFB (CFB Products)

Synonyms: AHUS4 antibody, BF antibody, BFD antibody, CFAB antibody, FB antibody, FBI12 antibody, GBG antibody, H2-Bf antibody, PBF2 antibody, bf antibody, Bf-1 antibody, Brre-Bf antibody, zgc:114032 antibody, Bf antibody, Sp152 antibody, bfb-A antibody, Bf B antibody, LOC397725 antibody, bf/c2 antibody, CFB antibody, AI195813 antibody, AI255840 antibody, B antibody, C2 antibody, Fb antibody, Da1-24 antibody, complement factor B antibody, complement factor B S homeolog antibody, complement factor B L homeolog antibody, CFB antibody, cfb antibody, bf antibody, cfb.S antibody, cfb.L antibody, bf/c2 antibody, LOC100555981 antibody, Cfb antibody

Background:

Background: Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.

Aliases: AHUS4 antibody, B factor properdin antibody, BF antibody, BFD antibody, C3 proaccelerator antibody, C3 proactivator antibody, C3/C5 convertase antibody, CFAB antibody, CFAB_HUMAN antibody, CFB antibody, Complement Factor B antibody, Complement factor B Bb fragment antibody, FB antibody, FBI12 antibody, GBG antibody, Glycine rich beta glycoprotein antibody, Glycine-rich beta glycoprotein antibody, H2 Bf antibody, H2BF antibody, PBF2 antibody, Properdin factor B antibody

UniProt: P00751

Pathways: Complement System, Proton Transport, Ribonucleoside Biosynthetic Process