LTBP4 antibody (N-Term)
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- Target See all LTBP4 Antibodies
- LTBP4 (Latent Transforming Growth Factor beta Binding Protein 4 (LTBP4))
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Binding Specificity
- N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LTBP4 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- Cross-Reactivity
- Human, Mouse
- Characteristics
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Rabbit Polyclonal antibody to LTBP4 (latent transforming growth factor beta binding protein 4)
LTBP4 antibody [N1N2], N-term - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the N-terminus region of human LTBP4. The exact sequence is proprietary.
- Isotype
- IgG
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- Application Notes
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: Mouse brain , Positive Control: Mouse brain
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.07 mg/mL
- Buffer
- 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- LTBP4 (Latent Transforming Growth Factor beta Binding Protein 4 (LTBP4))
- Alternative Name
- latent transforming growth factor beta binding protein 4 (LTBP4 Products)
- Synonyms
- ARCL1C antibody, LTBP-4 antibody, LTBP4L antibody, LTBP4S antibody, 2310046A13Rik antibody, latent transforming growth factor beta binding protein 4 antibody, LTBP4 antibody, ltbp4 antibody, Ltbp4 antibody
- Background
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Transforming growth factor-beta, or TGFB (see TGFB1, MIM 190180), remains biologically latent after secretion, blocked from activity by its N-terminal propeptide (the latency-associated peptide, or LAP). TGFB is activated by its dissociation from LAP. The latent form of TGFB is secreted in association with a latent TGFB-binding protein, or LTBP (see LTBP1, MIM 150390), and assembled into the extracellular matrix. LTBPs are mainly composed of epidermal growth factor (EGF, MIM 131530)-like repeats and protein domains with 8-cysteine repeats, both of which are also found in fibrillins (e.g., MIM 134797). See Oklu and Hesketh (2000) [PubMed 11104663] for a review of the LTBP gene family.[supplied by OMIM]
Cellular Localization: Secreted , extracellular space , extracellular matrix - Molecular Weight
- 173 kDa
- Gene ID
- 8425
- UniProt
- Q8N2S1
- Pathways
- Hormone Transport, Growth Factor Binding
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