CYP17A1 antibody (Center)
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- Target See all CYP17A1 Antibodies
- CYP17A1 (Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1))
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Binding Specificity
- Center
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CYP17A1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Chimpanzee
- Cross-Reactivity (Details)
- Chimpanzee (100 %)
- Characteristics
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Rabbit Polyclonal antibody to CYP17A1 (cytochrome P450, family 17, subfamily A, polypeptide 1)
CYP17A1 antibody [N1C2] - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human CYP17A1. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product CYP17A1 Primary Antibody
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- Application Notes
- Suggested dilution Reference Western blot 1:500-1:20000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:20000*
- Comment
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Positive Control: NIH-3T3 , C2C12 , MCF-7 , HepG2
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.65 mg/mL
- Buffer
- 0.1M Tris, 0.1M Glycine, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- CYP17A1 (Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1))
- Alternative Name
- CYP17A1 (CYP17A1 Products)
- Synonyms
- cyp17 antibody, CYPXVII antibody, P450c17 antibody, cyp17a1 antibody, P450-C17 antibody, wu:fi13g04 antibody, wu:fi17b11 antibody, wu:fi31c08 antibody, zgc:136516 antibody, zgc:66494 antibody, P45017A1 antibody, CYP17 antibody, CPT7 antibody, P450C17 antibody, S17AH antibody, Cyp17 antibody, p450c17 antibody, cytochrome P450 17A1 antibody, cytochrome P450, family 17, subfamily A, polypeptide 1 antibody, steroidogenic cytochrome P450 17-hydroxylase/lyase antibody, cytochrome P450 family 17 subfamily A member 1 L homeolog antibody, cytochrome P450 family 17 subfamily A member 1 antibody, cytochrome P-450 17 alpha-hydroxylase/C17,20-lyase antibody, cytochrome P450, family 17, subfamily a, polypeptide 1 antibody, cytochrome P450c17 antibody, CpipJ_CPIJ010537 antibody, CpipJ_CPIJ010543 antibody, PTRG_02047 antibody, cyp17a1 antibody, cyp17 antibody, cyp17a1.L antibody, CYP17A1 antibody, Cyp17a1 antibody
- Background
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This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.
Cellular Localization: Membrane , Membrane, Single-pass membrane protein , Membrane , Membrane - Molecular Weight
- 57 kDa
- Gene ID
- 1586
- Pathways
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, C21-Steroid Hormone Metabolic Process, Cellular Response to Molecule of Bacterial Origin
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