GABRA1 antibody (Center)
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- Target See all GABRA1 Antibodies
- GABRA1 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1))
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Binding Specificity
- Center
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GABRA1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Rhesus Monkey, Cow (Bovine)
- Cross-Reactivity (Details)
- Rhesus Monkey (100 %), Bovine (100 %)
- Characteristics
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Rabbit polyclonal antibody to GABA A Receptor alpha 1 (gamma-aminobutyric acid (GABA) A receptor, alpha 1)
GABA A Receptor alpha 1 antibody [N1C1] - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human GABA A Receptor alpha 1. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product GABRA1 Primary Antibody
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- Application Notes
- Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
- Comment
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Positive Control: U87-MG , SK-N-SH
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.75 mg/mL
- Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- GABRA1 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1))
- Alternative Name
- GABA A Receptor alpha 1 (GABRA1 Products)
- Synonyms
- ECA4 antibody, EJM antibody, EJM5 antibody, zgc:153566 antibody, Gabra-1 antibody, gamma-aminobutyric acid type A receptor alpha1 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, alpha 1 antibody, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 antibody, gamma-aminobutyric acid receptor subunit alpha-1 antibody, GABRA1 antibody, Gabra1 antibody, gabra1 antibody, LOC100653509 antibody
- Background
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This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene.
Cellular Localization: Cell junction , synapse , postsynaptic cell membrane, Multi-pass membrane protein , Cell membrane, Multi-pass membrane protein - Molecular Weight
- 52 kDa
- Gene ID
- 2554
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