RASSF5 antibody (AA 313-329)

Catalog No. ABIN289515

Product Details anti-RASSF5 Antibody

Target: RASSF5 (Ras Association (RalGDS/AF-6) Domain Family Member 5 (RASSF5))

Binding Specificity: AA 313-329

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASSF5 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity (Details): This antibodys immunogen sequence is located in the RA domain of NORE1 and is 100 % conserved between human, rat and mouse.

Purification: Affinity chromatography purified

Immunogen: NORE1 antibody was raised in rabbit using AA 313-329 [DNPQKFALFKRIHKDGQ] of the NORE1 protein as the immunogen.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:1,000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Affinity purified IgG supplied in PBS with 0.02 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for RASSF5

Target: RASSF5 (Ras Association (RalGDS/AF-6) Domain Family Member 5 (RASSF5))

Alternative Name: NORE1 (RASSF5 Products)

Synonyms: Maxp1 antibody, NORE1 antibody, NORE1A antibody, NORE1B antibody, RAPL antibody, RASSF3 antibody, 1300019G20Rik antibody, AU042887 antibody, Nore1 antibody, Nore1A antibody, Nore1B antibody, Rapl antibody, Ras association domain family member 5 antibody, Ras association (RalGDS/AF-6) domain family member 5 antibody, RASSF5 antibody, Rassf5 antibody

Background: NORE1, which is structurally related to RASSF1, (a tumour-suppressor gene located at 3p21.3), can also mediate a Ras-dependent apoptosis. Moreover, an analysis of NORE1 protein expression showed that it is frequently down-regulated in lung tumor cell lines and primary lung tumors.

Pathways: TCR Signaling