RASSF5 antibody (AA 1-265)

Catalog No. ABIN7167138

The Rabbit Polyclonal anti-RASSF5 antibody is suitable to detect RASSF5 in samples from Human. It has been validated for WB, ELISA and IHC.

Quick Overview for RASSF5 antibody (AA 1-265) (ABIN7167138)

Target: RASSF5 (Ras Association (RalGDS/AF-6) Domain Family Member 5 (RASSF5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASSF5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-RASSF5 Antibody

Binding Specificity: AA 1-265

Purpose: RASSF5 Antibody

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Ras association domain-containing protein 5 protein (1-265AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RASSF5

Target: RASSF5 (Ras Association (RalGDS/AF-6) Domain Family Member 5 (RASSF5))

Alternative Name: RASSF5

Background:

Background: Potential tumor suppressor. Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing. May be involved in regulation of Ras apoptotic function. The RASSF5-STK4/MST1 complex may mediate HRAS and KRAS induced apoptosis.

Aliases: Maxp 1 antibody, MAXP1 antibody, MGC10823 antibody, MGC17344 antibody, New ras effector 1 antibody, NORE 1 antibody, NORE1 antibody, NORE1A antibody, NORE1B antibody, Novel Ras effector 1 antibody, RAP1 Binding Protein antibody, RAPL antibody, Ras association (RalGDS/AF 6) domain family 5 antibody, Ras association (RalGDS/AF 6) domain family member 5 antibody, Ras association domain containing family protein 5 antibody, Ras association domain-containing protein 5 antibody, Ras effector like protein antibody, RASF5_HUMAN antibody, RASSF 3 antibody, RASSF 5 antibody, RASSF3 antibody, RASSF5 antibody, Regulator for cell adhesion and polarization enriched in lymphoid tissue antibody, Regulator for cell adhesion and polarization enriched in lymphoid tissues antibody, Tumor suppressor RASSF3 antibody

UniProt: Q8WWW0

Pathways: TCR Signaling