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Transferrin Receptor (p90, CD71) (TFRC) antibody
| Antigen | Transferrin Receptor (p90, CD71) (TFRC) |
| Synonyms | TFR, CD71, TFR1, TRFR, TR, p90, Trfr, Mtvr1, Mtvr-1, AI195355, AI426448, AU015758, 2610028K12Rik, E430033M20Rik, TFRC, tfr, cd71, tfr1, trfr, DKFZp469M0811, LOC100219280 |
| Clonality | Monoclonal (YUK9) |
| Host |
 Alternatives Mouse |
| Reactivity |
Alternatives Human |
| Application |
Alternatives Flow Cytometry (FACS), Immunoprecipitation (IP)
|
| Catalog no. | ABIN290057 |
| Quantity | 50 ug (0.25 mg/ml) |
| Price | 942.65 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 7 to 10 Business Days |
Additional Information
| Alternative name | CD71 (TFRC) |
| Immunogen | human cancer cel line |
| Format | Affinity-purified |
| Isotype | IgG1 kappa (Matching secondary antibodies) |
| Clone | YUK9 |
| Description | CD71 (also known as TFRC: transferrin receptor) is a widely expressed 180 kDa type II membrane glycoprotein involved in the cellular uptake of iron and inthe regulation of cell growth. Iron uptake occurs via the internalization of iron-loaded transferrin mediated by the interaction with the CD71. CD71expression is increased on rapidly proliferating cells, while expression is decreased or absent on non-dividing cells. Some studies have suggested thatbiologically aggressive tumors require large amounts of iron for active metabolism and rapid cell growth, and overexpression of CD71 has reported indifferent types of cancers such as glioma, pancreatic, and colon cancers.In addition, CD71 is required for adult erythropoiesis and involved in T- and B- cell development. CD71 seems to play an important role in T cell activation,and T cells lacking CD71 are completely arrested at a very early stage of maturation.This antibody is specific to human CD71 and will be useful for FCM, immunoprecipitation. |
Application Details
| Application Notes | WB Not tested. IHC Not tested. ICC Not tested. ELISA Not tested. FCM 1.0-5.0 ug/ml. Neutralization Not tested. IP 5.0-10.0 ug/ml |
| Concentration | 0.25 mg/ml |
| Purification | Protein G |
| Buffer | PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat) |
| Storage | Store below -20 |
| Restrictions | For Research Use only |
Alternatives
Alternatives for antigen "Transferrin Receptor (p90, CD71) (TFRC)", type "Antibodies"
| Hosts | Mouse (100), Rat (25), Rabbit (8), Goat (1) |
| Reactivities | Human (88), Mouse (Murine) (29), Rat (Rattus) (12), Monkey (10) |
| Applications | Flow Cytometry (FACS) (86), Western Blotting (WB) (40), Immunoprecipitation (IP) (31), Immunohistochemistry (Frozen Sections) (IHC (fro)) (28), Enzyme Immunoassay (EIA) (26), ELISA (10), Immunofluorescence (IF) (8), Immunohistochemistry (IHC) (7), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (6), Functional Studies (Func) (4), ELISA (Capture) (3), ELISA (Detection) (3), Immunoelectron Microscopy (EM) (2) |
| Conjugates | Biotin (13), FITC (11), PE (11), APC (2), DY647 (1), SPRD (1) |
| Epitopes | extracellular domain (2), Ab-24 (1), N-Term (1), pSer24 (1) |
