TNFRSF10B antibody (Extracellular Domain) (FITC)

Catalog No. ABIN298144

This Mouse Monoclonal antibody specifically detects TNFRSF10B in FACS. It exhibits reactivity toward Human.

Quick Overview for TNFRSF10B antibody (Extracellular Domain) (FITC) (ABIN298144)

Target: TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNFRSF10B antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Clone: DR5-01-1

Product Details anti-TNFRSF10B Antibody (FITC)

Binding Specificity: Extracellular Domain

Specificity: Recognizes an extracellular domain of TRAIL-R2 (DR5). TRAIL-R2 is one of two TNF superfamily member intracellular death domain containing receptors for TRAIL (APO2L)

Purification: Protein A purified

Immunogen: Recombinant fusion protein of human IgG heavy chain and extracellular domain of DR5.

Type of Immunogen: Fusion protein

Isotype: IgG1

Application Details

Application Notes: Approved: Flo (1 - 10 μg/mL)

Usage: The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 5 μg/mL. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 15 mM sodium azide, 0.2 % high-grade protease free BSA as a stabilizing agent.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze. Product is photosensitive and should be protected from light.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze. Protect from light.

Target Details for TNFRSF10B

Target: TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))

Alternative Name: TNFRSF10B / Killer / DR5

Background: Name/Gene ID: TNFRSF10B
Family: TNF Receptor

Synonyms: TNFRSF10B, Cytotoxic TRAIL receptor-2, CD262 antigen, DR5, Death receptor 5, KILLER, TRAIL-R2, TRICK2B, TRAILR2, TRICK2A, TRICKB, TRICK2, CD262, Fas-like protein, TRAIL receptor 2, ZTNFR9

Gene ID: 8795

UniProt: O14763

Pathways: p53 Signaling, Apoptosis, Positive Regulation of Endopeptidase Activity