MAP2K4 antibody (pThr261)

Catalog No. ABIN3019509

Product Details anti-MAP2K4 Antibody

Target: MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))

Binding Specificity: pThr261

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP2K4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AKTRD

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Phosphorylated Antibodies

Immunogen: A synthetic phosphorylated peptide around T261 of human MAP2K4 (NP_003001.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-MAP2K4 antibody (ABIN3019509)

Li, Zhang, Zhu, Ashraf, Chen, Xu, Zhou, Zheng, Song, Chen, Ye, Cao: "Microarray Analysis Identifies the Potential Role of Long Non-Coding RNA in Regulating Neuroinflammation during Japanese Encephalitis Virus Infection." in: Frontiers in immunology, Vol. 8, pp. 1237, (2017) (PubMed).

Target Details for MAP2K4

Target: MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))

Alternative Name: MAP2K4 (MAP2K4 Products)

Synonyms: JNKK antibody, JNKK1 antibody, MAPKK4 antibody, MEK4 antibody, MKK4 antibody, PRKMK4 antibody, SAPKK-1 antibody, SAPKK1 antibody, SEK1 antibody, SERK1 antibody, SKK1 antibody, Sek1 antibody, Serk1 antibody, MKK4A-l antibody, map2k4 antibody, zgc:136500 antibody, jnkk antibody, mek4 antibody, mkk4 antibody, sek1 antibody, jnkk1 antibody, serk1 antibody, xmek2 antibody, mapkk4 antibody, prkmk4 antibody, 142758_at antibody, CG9738 antibody, CT27508 antibody, D-MKK4 antibody, DMKK4 antibody, Dmel\\CG9738 antibody, JNKK2 antibody, Mpk4 antibody, SEK1/MKK4 antibody, dMKK4 antibody, dMkk4 antibody, hep antibody, ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4 antibody, ATMEK4 antibody, ATMKK4 antibody, F19C24.26 antibody, F19C24_26 antibody, MAP KINASE KINASE 4 antibody, mitogen-activated protein kinase kinase 4 antibody, MKK4B antibody, zgc:194486 antibody, mitogen-activated protein kinase kinase 4 antibody, mitogen-activated protein kinase kinase 4a antibody, MAP kinase kinase 4 antibody, mitogen activated protein kinase kinase 4 antibody, mitogen-activated protein kinase kinase 4b antibody, MAP2K4 antibody, Map2k4 antibody, map2k4a antibody, map2k4 antibody, Mkk4 antibody, MKK4 antibody, map2k4b antibody

Background: This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants.,MAP2K4,JNKK,JNKK1,MAPKK4,MEK4,MKK4,PRKMK4,SAPKK-1,SAPKK1,SEK1,SERK1,SKK1,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Kinase,Tyrosine kinases,ErbB-HER Signaling Pathway,MAPK-JNK Signaling Pathway,MAPK-P38 Signaling Pathway,Cell Biology & Developmental Biology,Cytoskeleton,Actins,TGF-b-Smad Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,IL-6 Receptor Signaling Pathway,Toll-like Receptor Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,Protein phosphorylation,MAP2K4

Molecular Weight: 44 kDa/45 kDa

Gene ID: 6416

UniProt: P45985

Pathways: MAPK Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling