EMR2 antibody (Extracellular Domain, N-Term)

Catalog No. ABIN302496

Product Details anti-EMR2 Antibody

Target: EMR2 (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 2 (EMR2))

Binding Specificity: Extracellular Domain, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EMR2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody detects EGF-Like Module-Containing Mucin-Like Receptor 2 (EMR2) at N-terminal extracellular domain.

Purification: Immunoaffinity chromatography

Immunogen: EMR2 antibody was raised against synthetic peptide from N-terminal extracellular domain of human EMR2.

Application Details

Application Notes: Immunohistochemistry on paraffin sections (2 - 24 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Target Details for EMR2

Target: EMR2 (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 2 (EMR2))

Alternative Name: CD312 / EMR2 (EMR2 Products)

Synonyms: EMR2 antibody, CD312 antibody, adhesion G protein-coupled receptor E2 antibody, ADGRE2 antibody, LOC484898 antibody

Background: EMR2 is an Orphan-B GPCR with an unknown ligand. EMR2 has five EGF-like domains in the extracellular domain and is highly homologous to CD97. Multiple isoforms of EMR2 are produced by alternative splicing.Synonyms: EGF-like module EMR2, EGF-like module-containing mucin-like hormone receptor-like 2

Gene ID: 30817

NCBI Accession: NP_038475

UniProt: Q9UHX3