Orexin antibody

Catalog No. ABIN303049

Product Details anti-Orexin Antibody

Target: Orexin (OX)

Reactivity: Human

Host: Sheep

Clonality: Polyclonal

Conjugate: This Orexin antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: This antibody recognizes Human Prepro-orexin (HCRT).

Purification: Ammonium Sulfate Precipitation

Application Details

Application Notes: Immunohistochemistry on frozen and paraffin sections. ELISA: 1: 200 - 1: 800.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 8.0 mg/mL

Buffer: PBS, pH 7.2, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for Orexin

Target: Orexin (OX)

Alternative Name: Orexin (OX Products)

Synonyms: orexin-A antibody, PPOX antibody, NRCLP1 antibody, OX antibody, hypocretin neuropeptide precursor antibody, hypocretin antibody, Hcrt antibody, HCRT antibody

Background: Orexin, or hypocretin (HCRT), is a hypothalamic neuropeptide precusor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, are mediators in the central feedback mechanism that regulates feeding behavior.Synonyms: HCRT, Hypocretin, OX, PPORX, PPOX

Gene ID: 3060

NCBI Accession: NP_001515

UniProt: O43612

Pathways: Synaptic Membrane, Feeding Behaviour