SOX1 antibody (Middle Region)
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- Target See all SOX1 Antibodies
- SOX1 (SRY (Sex Determining Region Y)-Box 1 (SOX1))
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Binding Specificity
- AA 215-248, Middle Region
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Reactivity
- Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SOX1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purpose
- Rabbit IgG polyclonal antibody for Transcription factor SOX-1(SOX1) detection. Tested with WB in Human,Mouse,Rat.
- Sequence
- QHPGAGGAHP HAHPAHPHPH HPHAHPHNPQ PMHR
- Cross-Reactivity (Details)
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Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - Characteristics
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Rabbit IgG polyclonal antibody for Transcription factor SOX-1(SOX1) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: SRY (sex determining region Y)-box 1
Protein Name: Transcription factor SOX-1 - Purification
- Immunogen affinity purified.
- Immunogen
- A synthetic peptide corresponding to a sequence in the middle region of Human SOX1(215-248aa QHPGAGGAHPHAHPAHPHPHHPHAHPHNPQPMHR), identical to the related mouse sequence.
- Isotype
- IgG
- Top Product
- Discover our top product SOX1 Primary Antibody
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- Application Notes
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human , The detection limit for SOX1 is approximately 0.1 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - Comment
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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Derivation and Identification of Motor Neurons from Human Urine-Derived Induced Pluripotent Stem Cells." in: Stem cells international, Vol. 2018, pp. 3628578, (2018) (PubMed).
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Derivation and Identification of Motor Neurons from Human Urine-Derived Induced Pluripotent Stem Cells." in: Stem cells international, Vol. 2018, pp. 3628578, (2018) (PubMed).
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- Target
- SOX1 (SRY (Sex Determining Region Y)-Box 1 (SOX1))
- Alternative Name
- SOX1 (SOX1 Products)
- Synonyms
- BB176347 antibody, Sox-1 antibody, XlSox1 antibody, xSox1 antibody, wu:fi38c08 antibody, wu:fj38h03 antibody, zgc:92865 antibody, SRY-box 1 antibody, SRY (sex determining region Y)-box 1 antibody, SRY-box 1 S homeolog antibody, SRY (sex determining region Y)-box 1b antibody, SRY box 1 antibody, SRY (sex determining region Y)-box 1a antibody, SOX1 antibody, Sox1 antibody, sox1.S antibody, sox1b antibody, sox1a antibody
- Background
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SOX1 (for Sex determining region Y-box 1), located in 13q34, is a transcription factor in the Sox protein family. It means that this intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development. SOX1 expression is restricted to neuroectodermin the tetrapod embryo. It is expressed particularly in the ventral striatum.
Synonyms: Sex determining region Y box 1 antibody|sox1 antibody|SOX1_HUMAN antibody|SRY antibody|SRY box containing gene 1 antibody|SRY related HMG box gene 1 antibody|Transcription factor Sox-1 antibody - Gene ID
- 6656
- UniProt
- O00570
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