RAB10 antibody (C-Term)

Catalog No. ABIN3043448

Product Details anti-RAB10 Antibody

Target: RAB10 (RAB10, Member RAS Oncogene Family (RAB10))

Binding Specificity: AA 153-185, C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB10 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Ras-related protein Rab-10(RAB10) detection. Tested with WB in Human,Mouse,Rat.

Sequence: AKANINIEKA FLTLAEDILR KTPVKEPNSE NVD

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Ras-related protein Rab-10(RAB10) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: RAB10, member RAS oncogene family
Protein Name: Ras-related protein Rab-10

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human RAB10 (153-185aa AKANINIEKAFLTLAEDILRKTPVKEPNSENVD), identical to the related mouse sequence, and different from the related rat sequence by one amino acid.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for RAB10

Target: RAB10 (RAB10, Member RAS Oncogene Family (RAB10))

Alternative Name: RAB10 (RAB10 Products)

Synonyms: AW107754 antibody, Ac1075 antibody, zgc:92757 antibody, rab10 antibody, RAB10, member RAS oncogene family antibody, RAB10, member RAS oncogene family L homeolog antibody, RAB10 antibody, Rab10 antibody, rab10 antibody, rab10.L antibody

Background: Ras-related protein Rab-10 is a protein that in humans is encoded by the RAB10 gene. RAB10 belongs to the RAS superfamily of small GTPases. And RAB proteins localize to exocytic and endocytic compartments and regulate intracellular vesicle trafficking. The RAB10 gene is mapped to chromosome 2p23.1-p22.3 by radiation hybrid analysis. It was found that the purified recombinant GAP domain of human AS160 showed GAP activity with RAB2A, RAB8A, RAB10, and RAB14, but not with 14 other RABs. Immunoblot analysis showed that these RABs associated with Glut4-positive vesicles in mouse adipocytes. Thereby, it concluded that AK160 functions as a RAB GAP and that RABs may participate in GLUT4 translocation.

Synonyms: GTP binding protein RAB10 antibody|Rab10 antibody|RAB10 member RAS oncogene family antibody|RAB10_HUMAN antibody|Ras related GTP binding protein antibody|Ras related GTP binding protein RAB10 antibody|Ras-related protein Rab-10 antibody

Gene ID: 10890

UniProt: P61026

Pathways: Asymmetric Protein Localization, SARS-CoV-2 Protein Interactome