VEGFD antibody (AA 89-205)
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- Target See all VEGFD (Figf) Antibodies
- VEGFD (Figf) (C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf))
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Binding Specificity
- AA 89-205
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This VEGFD antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purpose
- Rabbit IgG polyclonal antibody for Vascular endothelial growth factor D(FIGF) detection.Tested with WB, IHC-P in Human,Mouse,Rat.
- Cross-Reactivity (Details)
- No cross reactivity with other proteins.
- Characteristics
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Rabbit IgG polyclonal antibody for Vascular endothelial growth factor D(FIGF) detection.Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: c-fos induced growth factor (vascular endothelial growth factor D)(VEGF-D)
Protein Name: Vascular endothelial growth factor D - Purification
- Immunogen affinity purified.
- Immunogen
- E. coli-derived human VEGFD recombinant protein (Position: F89-R205). Human VEGFD shares 94% and 94.9% amino acid (aa) sequence identity with mouse and rat VEGFD, respectively.
- Isotype
- IgG
- Top Product
- Discover our top product Figf Primary Antibody
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- Application Notes
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - Comment
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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VEGF-D-enhanced lymph node metastasis of ovarian cancer is reversed by vesicular stomatitis virus matrix protein." in: International journal of oncology, Vol. 49, Issue 1, pp. 123-32, (2017) (PubMed).
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VEGF-D-enhanced lymph node metastasis of ovarian cancer is reversed by vesicular stomatitis virus matrix protein." in: International journal of oncology, Vol. 49, Issue 1, pp. 123-32, (2017) (PubMed).
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- Target
- VEGFD (Figf) (C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf))
- Alternative Name
- FIGF (Figf Products)
- Synonyms
- FIGF antibody, vegfd antibody, vegf-d antibody, VEGFD antibody, AI325264 antibody, VEGF-D antibody, Vegfd antibody, Vegf-d antibody, vascular endothelial growth factor D antibody, Vascular endothelial growth factor D antibody, VEGFD antibody, vegfd antibody, vegfd.L antibody, Vegfd antibody
- Background
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C-fos induced growth factor (FIGF) (or vascular endothelial growth factor D, VEGF-D) is a vascular endothelial growth factor that in humans is encoded by the FIGF gene. The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. Analyzing by Northern blotting, Yamada et al. (1997) symbolized VEGFD, was expressed as a 2.2-kb transcript with highest expression in lung, heart, small intestine, and fetal lung, and lower levels in skeletal muscle, colon, and pancreas. And Achen et al. (1998) concluded that VEGFD was most closely related to VEGFC by virtue of the presence of N- and C-terminal extensions that were not found in other VEGF family members. Stacker et al. (2001) showed that VEGFD can induce tumor angiogenesis through VEGFR2 and tumor lymphangiogenesis through VEGFR3, whereas VEGF, which does not activate VEGFR3, induces only tumor angiogenesis.
Synonyms: c-fos induced growth factor antibody|c-fos induced growth factor (vascular endothelial growth factor D) antibody|c-fos-induced growth factor antibody|FIGF antibody|Vascular endothelial growth factor D antibody|Vascular endothelial growth factor D precursor antibody| VEGF D antibody|VEGF-D antibody|VEGFD antibody|VEGFD_HUMAN antibody - Gene ID
- 2277
- UniProt
- O43915
- Pathways
- RTK Signaling
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