PPAP2A antibody

Catalog No. ABIN306892

Product Details anti-PPAP2A Antibody

Target: PPAP2A (Phosphatidic Acid Phosphatase Type 2A (PPAP2A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPAP2A antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Characteristics: EC 3.1.3.4, Lipid Phosphate Phosphatase 1, Phosphatidic acid phosphatase 2a,Broad-specificity phosphohydrolase that dephosphorylates exogenous bioactive glycerolipids and sphingolipids. It catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG), and is a pivotal regulator of lysophosphatidic acid (LPA) signaling in the cardiovascular system. It is a major enzyme responsible of dephosphorylating LPA in platelets, which terminates signaling actions of LPA. It may control circulating, and possibly also regulate localized, LPA levels resulting from platelet activation. It has little activity towards ceramide-1-phosphate (C-1-P) and sphingosine-1-phosphate (S-1-P). The relative catalytic efficiency is LPA > PA > S-1-P > C-1-P. Its down-regulation may contribute to the development of colon adenocarcinoma.

Immunogen: Synthetic peptide derived from the LPP1 protein

Isotype: IgG

Application Details

Application Notes: Antibody can be used for Western blotting (5-10 μg/mL). Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Handling

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details for PPAP2A

Target: PPAP2A (Phosphatidic Acid Phosphatase Type 2A (PPAP2A))

Alternative Name: Lysophospholipid Phosphatase (LPP) 1/1A (PPAP2A Products)

Synonyms: PPAP2A antibody, wun antibody, LLP1a antibody, LPP1 antibody, PAP-2a antibody, PAP2 antibody, Hic53 antibody, Hpic53 antibody, LPP-1 antibody, mPAP antibody, PAP2A antibody, PAP2a2 antibody, phospholipid phosphatase 1 antibody, phosphatidic acid phosphatase type 2A antibody, phospholipid phosphatase 1 L homeolog antibody, PLPP1 antibody, plpp1 antibody, Ppap2a antibody, plpp1.L antibody, Plpp1 antibody

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway