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F-Box and WD Repeat Domain Containing 7 (FBXW7) antibody

Antigen

F-Box and WD Repeat Domain Containing 7 (FBXW7)

Synonyms AGO, CDC4, FBW6, FBW7, FBX30, FBXW6, SEL10, FBXO30, SEL-10, FLJ16457, DKFZp686F23254, cdc4
Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Human

Application
Alternatives Western Blotting (WB)
Catalog no. ABIN307140
Quantity 100 ug  (1 mg/ml)
Price 250.00 $   Plus shipping costs $35.00
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Availability Ships within 5 to 7 Business Days

Additional Information

Alternative name FBXW7
Swiss-Prot Q969H0
Description Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Involved in the degradation of cyclin E, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1. Synonyms: F-box and WD-40 domain protein 7, FBXW7, CDC4.

Application Details

Application Notes Antibody can be used for Western blotting (1-5 ug/ml). Positive Control: Widely expressed in most human tissues..
Concentration 1 mg/ml
Storage Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles
Restrictions For Research Use only

Alternatives

Alternatives for antigen "F-Box and WD Repeat Domain Containing 7 (FBXW7)", type "Antibodies"
Hosts Rabbit (10), Mouse (5)
Reactivities Human (14)
Applications Western Blotting (WB) (15), Enzyme Immunoassay (EIA) (4), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), ELISA (2), ELISA (Detection) (2), Immunofluorescence (IF) (1)