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FBXW7 antibody

FBXW7 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN307140
  • Target See all FBXW7 Antibodies
    FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))
    Reactivity
    • 66
    • 35
    • 32
    • 16
    • 15
    • 14
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 54
    • 13
    Rabbit
    Clonality
    • 57
    • 10
    Polyclonal
    Conjugate
    • 36
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This FBXW7 antibody is un-conjugated
    Application
    • 56
    • 24
    • 17
    • 14
    • 13
    • 12
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Human
    Characteristics
    F-box and WD-40 domain protein 7, FBXW7, CDC4,Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Involved in the degradation of cyclin E, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1.
    Purification
    Ammonium Sulfate Precipitation
    Immunogen
    Synthetic peptide dervied from the human FBXW7 protein
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    Discover our top product FBXW7 Primary Antibody
  • Application Notes
    Antibody can be used for Western blotting (1-5 μg/mL). Optimal concentration should be evaluated by serial dilutions.
    Restrictions
    For Research Use only
  • Buffer
    Provided as solution in phosphate buffered saline with 0.08 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
  • Target
    FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))
    Alternative Name
    FBXW7 (FBXW7 Products)
    Synonyms
    cdc4 antibody, AGO antibody, CDC4 antibody, FBW6 antibody, FBW7 antibody, FBX30 antibody, FBXO30 antibody, FBXW6 antibody, SEL-10 antibody, SEL10 antibody, hAgo antibody, hCdc4 antibody, 1110001A17Rik antibody, Cdc4 antibody, Fbw7 antibody, Fbwd6 antibody, Fbx30 antibody, Fbxo30 antibody, Fbxw6 antibody, F-box and WD repeat domain containing 7 antibody, F-box and WD-40 domain protein 7 antibody, Fbxw7 antibody, FBXW7 antibody, fbxw7 antibody
    UniProt
    Q969H0
    Pathways
    Notch Signaling, EGFR Signaling Pathway
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