Poly(A) Binding Protein Interacting Protein 1 (PAIP1) (N-Term) antibody

Details for Product No. ABIN310064
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Antigen
Synonyms fb53g01, zgc:91954, wu:fb53g01
Epitope
N-Term
(9), (9), (3), (2), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine), Human
(24), (5), (5), (2), (1), (1), (1)
Host
Rabbit
(19), (5)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(24), (13), (3), (2), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN310064
289.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human PAIP1
Sequence MSDGFDRAPE QTRPLRAPPS SQDKIPQQNS ESAMAKPQVV VAPVLMSKLS
Predicted Reactivity Human : 100 %, Mouse : 100 %, Rat : 100 %, Guinea pig : 90 %, Dog : 80 %, Bovine : 80 %, Horse : 70 %, Pig : 70 %
Characteristics This is a rabbit polyclonal antibody against PAIP1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name PAIP1
Background PAIP1 interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis. Overexpression of this gene in COS7 cells stimulates translation.The protein encoded by this gene interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis. Overexpression of this gene in COS7 cells stimulates translation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.The protein encoded by this gene interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis. Overexpression of this gene in COS7 cells stimulates translation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.
Molecular Weight 46 kDa
Gene ID 10605
NCBI Accession NP_877590, NM_182789
Research Area Chromatin and Nuclear Signaling, DNA/RNA
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 400 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Product cited in: Fortna, Kim, MacLaren et al.: "Lineage-specific gene duplication and loss in human and great ape evolution." in: PLoS biology, Vol. 2, Issue 7, pp. E207, 2004 (PubMed).

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