Cleavage and Polyadenylation Specific Factor 2, 100kDa (CPSF2) (N-Term) antibody

Details for Product No. ABIN310084
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Antigen
Synonyms
100kDa, 2610024B04Rik, AI662483, Cpsf, MCPSF, mKIAA1367, zgc:92484, CPSF100, cpsf2-A, ATCPSF100, CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR, CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR 100, E ... show more
100kDa, 2610024B04Rik, AI662483, Cpsf, MCPSF, mKIAA1367, zgc:92484, CPSF100, cpsf2-A, ATCPSF100, CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR, CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR 100, EMB1265, EMBRYO DEFECTIVE 1265, ENHANCED SILENCING PHENOTYPE 5, ESP5, cleavage and polyadenylation specificity factor 100 show less
Epitope
N-Term
(2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Xenopus laevis, Zebrafish (Danio rerio), Cow (Bovine), Dog (Canine), Human, Chicken
(16), (3), (3), (1), (1)
Host
Rabbit
(13), (5)
Clonality
Polyclonal
Application
Western Blotting (WB)
(13), (4), (4), (3), (3), (3), (2), (1), (1)
Pubmed 1 reference available
Quantity 50 µg
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Catalog No. ABIN310084
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Immunogen Synthetic peptide directed towards the N terminal of human CPSF2
Sequence YAVGKLGLNC AIYATIPVYK MGQMFMYDLY QSRHNTEDFT LFTLDDVDAA
Predicted Reactivity African clawed frog : 100 %, Bovine : 100 %, Chicken : 100 %, Dog : 100 %, Human : 100 %, Mouse : 100 %, Rat : 100 %, Zebrafish : 100 %
Characteristics This is a rabbit polyclonal antibody against CPSF2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name CPSF2
Background CPSF2 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. It belongs to the metallo-beta-lactamase superfamily, RNA-metabolizing metallo-beta-lactamase-like family, CPSF2/YSH1 subfamily.
Molecular Weight 88 kDa
Gene ID 53981
NCBI Accession NP_059133, NM_017437
UniProt Q9P2I0
Research Area Chromatin and Nuclear Signaling, Chromatin Binding Proteins, DNA/RNA
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 782 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Product cited in: Ewing, Chu, Elisma et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, 2007 (PubMed).

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