SLC12A2 antibody (C-Term)

Catalog No. ABIN310505

There are 2+ publications for this product available. The Rabbit Polyclonal anti-SLC12A2 antibody is suitable to detect SLC12A2 in samples from Human, Rat, Mouse, Cow, Dog, Pig, Horse, Guinea Pig, Rabbit and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for SLC12A2 antibody (C-Term) (ABIN310505)

Target: SLC12A2 (Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 2 (SLC12A2))

Reactivity: Human, Rat, Mouse, Cow, Dog, Pig, Horse, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC12A2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SLC12A2 Antibody

Binding Specificity: C-Term

Sequence: IIAFEEIIEP YRLHEDDKEQ DIADKMKEDE PWRITDNELE LYKTKTYRQI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against SLC12A2. It was validated on Western Blot.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SLC12A2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1212 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SLC12A2 antibody (ABIN310505)

Jansen, Peugh, Roden, Ojemann: "Impaired maturation of cortical GABA(A) receptor expression in pediatric epilepsy." in: Epilepsia, Vol. 51, Issue 8, pp. 1456-67, (2010) (PubMed).

Chen, Sun, Deng, Hao, Chen, Xing, Jia, Ma, Wei, Zhu, Qian, Jiang, He: "Quantitative proteome analysis of HCC cell lines with different metastatic potentials by SILAC." in: Proteomics, Vol. 8, Issue 23-24, pp. 5108-18, (2008) (PubMed).

Target Details for SLC12A2

Target: SLC12A2 (Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 2 (SLC12A2))

Alternative Name: SLC12A2

Background: By moving chloride into epithelial cells, the Na-K-Cl cotransporter SLC12A2 aids transcellular movement of chloride across both secretory and absorptive epithelia.By moving chloride into epithelial cells, the Na-K-Cl cotransporter SLC12A2 aids transcellular movement of chloride across both secretory and absorptive epithelia (Payne et al., 1995). See also SLC12A1 (MIM 600839) and SLC12A3 (MIM 600968).[supplied by OMIM].
Alias Symbols: BSC, BSC2, MGC104233, NKCC1
Protein Interaction Partner: EGFR, MDM2, ATP4A, COMMD1, UBC, SEC13, STK39, OXSR1, SLC12A2, MAPK14,
Protein Size: 1212

Molecular Weight: 131 kDa

Gene ID: 6558

NCBI Accession: NM_001046, NP_001037

UniProt: P55011

Pathways: Sensory Perception of Sound