anti-ADAM7 antibody (ADAM Metallopeptidase Domain 7) (C-Term)

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Antigen
Synonyms ADAM7, 9230104J12Rik, EAP1, EAPI, ADAM 7, ADAM-7, GP-83, GP83, 7, ADAM, EAP, EAP I, I
Alternatives
Epitope
C-Term
(4), (1), (1)
Reactivity
Dog (Canine), Human, Mouse (Murine)
(8), (3), (2), (1)
Host
Rabbit
(7), (1)
Clonality
Polyclonal
Application
Western Blotting (WB)
(6), (3), (2)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the C terminal of human ADAM7
Blocking Peptide Blocking peptide for this product available: ADAM Metallopeptidase Domain 7 (ADAM7) peptide (ABIN972906)
Sequence PTETLGVENK GYFGDEQQIR TEPILPEIHF LNKPASKDSR GIADPNQSAK
Predicted Reactivity Human : 100 %, Mouse : 90 %, Dog : 80 %, Horse : 80 %
Characteristics This is a rabbit polyclonal antibody against ADAM7. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name ADAM7 (ADAM7 Antibody Abstract)
Background The ADAM family is composed of zinc-binding proteins that can function as adhesion proteins and/or endopeptidases. They are involved in a number of biologic processes, including fertilization, neurogenesis, muscle development, and immune response.The ADAM family is composed of zinc-binding proteins that can function as adhesion proteins and/or endopeptidases. They are involved in a number of biologic processes, including fertilization, neurogenesis, muscle development, and immune response.
Molecular Weight 83 kDa
Gene ID 8756
NCBI Accession NM_003817, NP_003808
UniProt Q9H2U9
Research Area Proteolysis / Ubiquitin, Metalloprotease, Extracellular Matrix
Pathways Notch Signaling
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 754 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-ADAM7 antibody (ADAM Metallopeptidase Domain 7) (C-Term) (ABIN311605) WB Suggested Anti-ADAM7 Antibody Titration: 0.2-1 ug/ml
Positive Control...
Background publications Seals, Courtneidge: "The ADAMs family of metalloproteases: multidomain proteins with multiple functions." in: Genes & development, Vol. 17, Issue 1, pp. 7-30, 2003 (PubMed).

Catalog No. ABIN311605
$289.00
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