ATG5 Autophagy Related 5 Homolog (S. Cerevisiae) (ATG5) (C-Term) antibody

Details for Product No. ABIN311668
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Antigen
Synonyms
ATG5, CG1643, DmAtg5, Dmel\\CG1643, atg5, apg5l, zgc:100934, ATATG5, AUTOPHAGY 5, MKP11.20, MKP11_20, APG5, APG5-LIKE, APG5L, ASP, hAPG5, 2010107M05Rik, 3110067M24Rik, AW319544, Apg5l, Atg5l, C88337,  ... show more
ATG5, CG1643, DmAtg5, Dmel\\CG1643, atg5, apg5l, zgc:100934, ATATG5, AUTOPHAGY 5, MKP11.20, MKP11_20, APG5, APG5-LIKE, APG5L, ASP, hAPG5, 2010107M05Rik, 3110067M24Rik, AW319544, Apg5l, Atg5l, C88337, Paddy show less
Epitope
C-Term
(37), (16), (10), (8), (4), (4), (4), (4), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Xenopus laevis, Cow (Bovine), Human
(145), (68), (53), (22), (20), (13), (12), (7), (6), (6), (2), (1), (1), (1), (1)
Host
Rabbit
(105), (31), (12), (3), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(5), (5), (5), (4), (4), (4), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(132), (76), (70), (23), (17), (10), (7), (4), (3), (3), (1)
Pubmed 1 reference available
Quantity 50 µg
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Catalog No. ABIN311668
289.00 $
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Immunogen Synthetic peptide directed towards the C terminal of human ATG5
Sequence DPEDGEKKNQ VMIHGIEPML ETPLQWLSEH LSYPDNFLHI SIIPQPTD
Predicted Reactivity African clawed frog : 100 %, Bovine : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rabbit : 100 %, Rat : 100 %, Chicken : 90 %, Zebrafish : 90 %
Characteristics This is a rabbit polyclonal antibody against ATG5. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name ATG5
Background ATG5 is required for autophagy. It conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. ATG5 may play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.
Molecular Weight 32 kDa
Gene ID 9474
NCBI Accession NM_004849, NP_004840
UniProt Q9H1Y0
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 275 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-ATG5 Autophagy Related 5 Homolog (S. Cerevisiae) (ATG5) (C-Term) antibody anti-ATG5 Autophagy Related 5 Homolog (S. Cerevisiae) (ATG5) (C-Term) antibody
anti-ATG5 Autophagy Related 5 Homolog (S. Cerevisiae) (ATG5) (C-Term) antibody (2) anti-ATG5 Autophagy Related 5 Homolog (S. Cerevisiae) (ATG5) (C-Term) antibody (Image 2)
anti-ATG5 Autophagy Related 5 Homolog (S. Cerevisiae) (ATG5) (C-Term) antibody (3) anti-ATG5 Autophagy Related 5 Homolog (S. Cerevisiae) (ATG5) (C-Term) antibody (Image 3)
Product cited in: Ewing, Chu, Elisma et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry." in: Molecular systems biology, Vol. 3, pp. 89, 2007 (PubMed).

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