EPH Receptor A2 antibody (EPHA2) (AA 559-976)

Details for Product anti-EPHA2 Antibody No. ABIN317512, Supplier: Log in to see
Antigen
  • EPHA2
  • epha2
  • MGC89505
  • ARCC2
  • CTPA
  • CTPP1
  • CTRCT6
  • ECK
  • AW545284
  • Eck
  • Myk2
  • Sek-2
  • Sek2
  • EPH receptor A2
  • EphA2
  • epoxide hydrolase
  • Eph receptor A2
  • EPHA2
  • epha2
  • ephA2
  • Epha2
Alternatives
anti-Human EPH Receptor A2 antibody for Flow Cytometry
Epitope
AA 559-976
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Reactivity
Human, Mouse (Murine)
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Host
Mouse
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Clonality (Clone)
Monoclonal ()
Conjugate
This EPH Receptor A2 antibody is un-conjugated
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Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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27
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5
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Options
Supplier
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Immunogen Recombinant human EphA2 (559-976 aa) purified from E. coli
Clone 3D7
Isotype IgG2b
Specificity The antibody recognizes Human and Mouse EPHA2. Other species not tested.
Characteristics Synonyms: Ephrin type-A receptor 2, Epithelial cell kinase, Eph receptor A2, Tyrosine-protein kinasereceptor ECK
Purification Protein-G affinity chromatography
Alternative Name EPHA2 / ECK (EPHA2 Antibody Abstract)
Background The Eph family of receptors is the largest known subfamily of receptor tyrosine kinases (RTK). Eph RTKs and their ligands, the ephrins, are frequently overexpressed in a variety of cancers and tumor cell lines. One Eph family member, EphA2, is also overexpressed in a wide variety of cancers, including breast, small-cell lung and gastrointestinal cancers, melanomas, and neuroblastomas. The ephrin-Eph interactions are important in development, especially in cell-cell interactions involved in nervous system patterning and possibly in cancer.Synonyms: Eph receptor A2, Ephrin type-A receptor 2, Epithelial cell kinase, Tyrosine-protein kinase receptor ECK
Gene ID 1969
UniProt P29317
Pathways RTK Signaling
Application Notes ELISA. Western blot (1: 500 - 2,000). Immunohistochemistry (1: 100 - 1: 200).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS, pH 7.4, containing 0.09 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Expiry Date 12 months
Supplier Images
Western Blotting (WB) image for anti-EPH Receptor A2 (EPHA2) (AA 559-976) antibody (ABIN317512) anti-EPH Receptor A2 (EPHA2) (AA 559-976) antibody
Immunohistochemistry (IHC) image for anti-EPH Receptor A2 (EPHA2) (AA 559-976) antibody (ABIN317512) anti-EPH Receptor A2 (EPHA2) (AA 559-976) antibody (Image 2)
Immunohistochemistry (IHC) image for anti-EPH Receptor A2 (EPHA2) (AA 559-976) antibody (ABIN317512) anti-EPH Receptor A2 (EPHA2) (AA 559-976) antibody (Image 3)
Immunohistochemistry (IHC) image for anti-EPH Receptor A2 (EPHA2) (AA 559-976) antibody (ABIN317512) anti-EPH Receptor A2 (EPHA2) (AA 559-976) antibody (Image 4)
Western Blotting (WB) image for anti-EPH Receptor A2 (EPHA2) (AA 559-976) antibody (ABIN317512) anti-EPH Receptor A2 (EPHA2) (AA 559-976) antibody (Image 5)
Immunohistochemistry (IHC) image for anti-EPH Receptor A2 (EPHA2) (AA 559-976) antibody (ABIN317512) anti-EPH Receptor A2 (EPHA2) (AA 559-976) antibody (Image 6)
Background publications Ireton, Chen: "EphA2 receptor tyrosine kinase as a promising target for cancer therapeutics." in: Current cancer drug targets, Vol. 5, Issue 3, pp. 149-57, 2005 (PubMed).

Nakamoto, Bergemann: "Diverse roles for the Eph family of receptor tyrosine kinases in carcinogenesis." in: Microscopy research and technique, Vol. 59, Issue 1, pp. 58-67, 2002 (PubMed).

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