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WHSC1L1 antibody (Wolf-Hirschhorn Syndrome Candidate 1-Like 1) (AA 383-660)

Details for Product anti-WHSC1L1 Antibody No. ABIN317544, Supplier: Log in to see
Antigen
  • WHSC1L1
  • NSD3
  • pp14328
  • 6720429E03
  • A530023P05
  • AI528490
  • WHISTLE
Epitope
AA 383-660
14
7
6
3
3
2
2
1
Reactivity
Human
51
8
5
Host
Mouse
37
14
Clonality (Clone)
Monoclonal ()
Conjugate
This WHSC1L1 antibody is un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
43
27
12
8
1
1
Supplier
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Immunogen Recombinant human NSD3 (383-660 aa) purified from E. coli
Clone 2-00E-009
Isotype IgG2b
Specificity The antibody recognizes human NSD3. Other species not tested.
Characteristics Synonyms: Wolf-Hirschhorn syndrome candidate 1-like protein 1, Whistle, DC28, Histone-lysineN-methyltransferase NSD3, Nuclear SET domain-containing protein 3, WHSC1-like protein 1,WHSC1-like 1 isoform 9 with methyltransferase activity to lysine
Purification Protein-G Affinity Chromatography
Alternative Name WHSC1L1 / NSD3 (WHSC1L1 Antibody Abstract)
Background This gene encoding NSD3 is related to the Wolf-Hirschhorn syndrome candidate - 1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. NSD3 is a Histone methyltransferase which preferentially methylates 'Lys-4' and 'Lys-27' of histone H3 and is amplified in several tumor cell lines and primary breast carcinomas.Synonyms: DC28, Histone-lysine N-methyltransferase NSD3, Nuclear SET domain-containing protein 3, WHSC1-like 1 isoform 9 with methyltransferase activity to lysine, WHSC1-like protein 1, Whistle, Wolf-Hirschhorn syndrome candidate 1-like protein 1
Gene ID 54904
UniProt Q9BZ95
Application Notes ELISA. Western blot (1: 1,000 - 1: 3,000), recommended starting dilution is 1: 2,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS, pH 7.4, 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Expiry Date 12 months
Supplier Images
Western Blotting (WB) image for anti-WHSC1L1 antibody (Wolf-Hirschhorn Syndrome Candidate 1-Like 1) (AA 383-660) (ABIN317544) anti-Wolf-Hirschhorn Syndrome Candidate 1-Like 1 (WHSC1L1) (AA 383-660) antibody
Background publications Angrand, Apiou, Stewart et al.: "NSD3, a new SET domain-containing gene, maps to 8p12 and is amplified in human breast cancer cell lines." in: Genomics, Vol. 74, Issue 1, pp. 79-88, 2001 (PubMed).

Stec, Nagl, van Ommen et al.: "The PWWP domain: a potential protein-protein interaction domain in nuclear proteins influencing differentiation?" in: FEBS letters, Vol. 473, Issue 1, pp. 1-5, 2000 (PubMed).