CLCC1 antibody
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- Target See all CLCC1 Antibodies
- CLCC1 (Chloride Channel CLIC-Like 1 (CLCC1))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CLCC1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Specificity
- This antibody detects endogenous levels of CLCC1 protein.(region surrounding Asp429)
- Purification
- Affinity Chromatography using epitope-specific immunogen
- Top Product
- Discover our top product CLCC1 Primary Antibody
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- Application Notes
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ELISA: 1/40000approx. 1/60000. Western Blot: 1/500approx. 1/1000. Immunofluorescence: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS) pH ~7.2, 0.05 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- CLCC1 (Chloride Channel CLIC-Like 1 (CLCC1))
- Alternative Name
- CLCC1 (CLCC1 Products)
- Synonyms
- CLCC1 antibody, clcc1 antibody, MCLC antibody, Mclc antibody, chloride channel CLIC like 1 antibody, Chloride channel CLIC-like protein 1 antibody, chloride channel CLIC-like 1 antibody, chloride channel CLIC-like 1 S homeolog antibody, CLCC1 antibody, clcc1 antibody, Clcc1 antibody, clcc1.S antibody
- Background
- Chloride channels (CLCs) regulate cellular traffic of chloride ions, a critical component of all living cells. CLCs are involved in membrane potential stabilization, signal transduction, cell volume regulation and organic solute transport. CLCC1 (Chloride channel CLIC-like protein 1), also known as MCLC (Mid-1-related chloride channel) or KIAA0761, is a 551 amino acid multi-pass membrane protein that belongs to the chloride channel MCLC family. CLCC1 is related to the Saccharomyces cerevisiaeprotein Mid-1 and is believed to function as an intracellular chloride channel that is expressed in lung, brain, muscle, liver and testis. Localizing to intracellular compartments such as the Golgi apparatus, the endoplasmic reticulum (ER) and the nuclear envelope, CLCC1 is expressed as four isoforms due to alternative splicing events, namely hMCLC-1, hMCLC-2, hMCLC-3 and hMCLC-4.Synonyms: Chloride channel CLIC-like protein 1, KIAA0761, MCLC, Mid-1-related chloride channel protein 1
- Molecular Weight
- approx. 62 kDa
- Gene ID
- 23155
- NCBI Accession
- NP_001041675
- UniProt
- Q96S66
- Pathways
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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