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CD14 antibody (APC)

CD14 Reactivity: Human, Monkey FACS Host: Mouse Monoclonal UCHM1 APC
Catalog No. ABIN319682
  • Target See all CD14 Antibodies
    CD14
    Reactivity
    • 247
    • 47
    • 30
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    Human, Monkey
    Host
    • 204
    • 64
    • 16
    • 3
    • 1
    Mouse
    Clonality
    • 224
    • 64
    Monoclonal
    Conjugate
    • 121
    • 29
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    • 2
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    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
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    This CD14 antibody is conjugated to APC
    Application
    • 202
    • 99
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    Flow Cytometry (FACS)
    Purification
    Affinity chromatography on Protein G
    Immunogen
    Human Thymocytes followed by peripheral blood mononuclear cells. Spleen cells from an immunised mouse were fused with cells of a mouse myeloma line.
    Clone
    UCHM1
    Isotype
    IgG2a
    Top Product
    Discover our top product CD14 Primary Antibody
  • Application Notes
    Flow Cytometry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Reconstitution
    Restore with 1 mL distilled water
    Buffer
    PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % Bovine Serum Albumin as stabilizer.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    This product is photosensitive and should be protected from light
    Storage
    4 °C
    Storage Comment
    Prior to and following reconstitution store the antibody at 2-8 °C. DO NOT FREEZE!
  • Target
    CD14
    Alternative Name
    CD14 (CD14 Products)
    Synonyms
    CD14 molecule antibody, CD14 antigen antibody, CD14 antibody, Cd14 antibody
    Background
    CD14 is a single copy gene encoding 2 protein forms: a 50 to 55 kDa glycosylphosphatidylinositol anchored membrane protein (mCD14) and a monocyte or liver derived soluble serum protein (sCD14) that lacks the anchor. Both molecules are critical for lipopolysaccharide (LPS) dependent signal transduction, and sCD14 confers LPS sensitivity to cells lacking mCD14. Increased sCD14 levels are associated with inflammatory infectious diseases and high mortality in gram negative shock. CD14 also appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.Synonyms: Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein
    Gene ID
    9606
    UniProt
    P08571
    Pathways
    TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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