FGFR3 antibody (N-Term)

Catalog No. ABIN329853

Product Details anti-FGFR3 Antibody

Target: FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))

Binding Specificity: AA 792-806, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGFR3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Does not react with human FGFR1 or FGFR2. Species cross-reactivity: Human. Not yet tested in other species.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Monkey (94%) Horse (88%) Panda, Bovine (81%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide: KDLLPPAPPSSGGSRT, corresponding to amino acids 792-806 of the cytoplasmic region of Human FGFR3 with N-terminal added lysine. The peptide is conjugated to KLH with glutaraldehyde. Percent identity by BLAST analysis: Human, Monkey (94%), Horse (88%), Panda, Bovine (81%).

Type of Immunogen: Synthetic peptide - KLH conjugated

Isotype: IgG

Application Details

Application Notes: Approved: IHC, IHC-P, IP, WB

Usage: Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry (paraffin-embedded sections). Positive control: Whole cell lysates of transfected 293T (embryonic kidney) cells expressing recombinant human FGFR3.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 1 % BSA, 15 mM sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Target Details for FGFR3

Target: FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))

Alternative Name: FGFR3 (FGFR3 Products)

Synonyms: FGFR3 antibody, LOC100034114 antibody, ACH antibody, CD333 antibody, CEK2 antibody, HSFGFR3EX antibody, JTK4 antibody, FR3 antibody, Fgfr-3 antibody, Flg-2 antibody, HBGFR antibody, Mfr3 antibody, sam3 antibody, fc27h01 antibody, wu:fc27h01 antibody, fibroblast growth factor receptor 3 antibody, fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) S homeolog antibody, FGFR3 antibody, fgfr3.S antibody, Fgfr3 antibody, fgfr3 antibody

Background: Name/Gene ID: FGFR3
Subfamily: FGF Receptor
Family: Protein Kinase

Synonyms: FGFR3, CD333, CD333 antigen, ACH, FGF receptor 3, HSFGFR3EX, Hydroxyaryl-protein kinase, JTK4, FGFR-3, CEK2, Tyrosine kinase JTK4

Gene ID: 2261

UniProt: P22607

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Growth Factor Binding