Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4) antibody

Antigen: Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4)

Synonyms: BAR, FXR, HRR1, HRR-1, RIP14, MGC163445, Fxr, Rxrip14, AI957360, MGC94878, MGC110190, zgc:92742, zgc:110190, NR1H4, MGC127466

Clonality: Polyclonal

Host: Goat

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN334396

Additional Information

Alternative name: Farnesoid X receptor / HRR1

Gene ID: 9971

Immunogen: KSCREKTELTPDQQ

Description: All names and symbols: farnesoid X receptor, HRR1, NR1H4, nuclear receptor subfamily 1, group H, member 4 , BAR, FXR, HRR-1, RIP14 , farnesol receptor HRR-1. Official Symbol: NR1H4. RefSeq number(s): NP_005114.1

Specificity: Human, Dog

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:32,000. Western Blot: Approx 55kDa band observed in Human Duodenum and Human Lung lysates (calculated MW of 54.4kDa according to NP_005114.1). Recommended concentration: 1-3µg/ml.

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Restrictions: For Research Use only

Images

ABIN334396 (1µg/ml) staining of Human Lung lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Publications

Publications: Huang, Ma, Zhang et al.: "Nuclear receptor-dependent bile acid signaling is required for normal liver regeneration." in: Science (New York, N.Y.), Vol. 312, Issue 5771, pp. 233-6, 2006 (PubMed).