NR1H4 antibody (AA 194-243)
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- Target See all NR1H4 Antibodies
- NR1H4 (Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))
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Binding Specificity
- AA 194-243
- Reactivity
- Human, Rat, Mouse, Dog, Horse, Cow, Pig, Guinea Pig, Monkey, Bat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NR1H4 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Brand
- IHC-plus™
- Specificity
- Human NR1H4
- Predicted Reactivity
- Percent identity by BLAST analysis: Human, Mouse, Rat, Dog, Bovine, Horse, Pig, Guinea pig (100%) Rabbit (92%) Chicken (85%).
- Purification
- Immunoaffinity purified
- Immunogen
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Synthetic peptide located between aa194-243 of human NR1H4 (Q96RI1-2, NP_005114). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Elephant, Dog, Bovine, Bat, Horse, Pig, Guinea pig (100%), Hamster, Rabbit (92%), Turkey, Chicken (85%), Platypus (84%), M. tuberculosis (83%).
Type of Immunogen: Synthetic peptide - Top Product
- Discover our top product NR1H4 Primary Antibody
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- Application Notes
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Approved: IHC, IHC-P (5 μg/mL), WB (0.2 - 1 μg/mL)
Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with 50 μL of distilled water
- Concentration
- Lot specific
- Buffer
- Lyophilized from PBS with 2 % sucrose
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
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- Target
- NR1H4 (Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))
- Alternative Name
- NR1H4 / FXR (NR1H4 Products)
- Synonyms
- zgc:110190 antibody, zgc:92742 antibody, NR1H4 antibody, BAR antibody, FXR antibody, HRR-1 antibody, HRR1 antibody, RIP14 antibody, AI957360 antibody, Fxr antibody, Rxrip14 antibody, nuclear receptor subfamily 1, group H, member 5 S homeolog antibody, nuclear receptor subfamily 1, group H, member 4 antibody, nuclear receptor subfamily 1 group H member 4 antibody, nr1h5.S antibody, nr1h4 antibody, NR1H4 antibody, Nr1h4 antibody
- Background
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Name/Gene ID: NR1H4
Subfamily: NR1 Thyroid hormone-like
Family: NHR
Synonyms: NR1H4, BAR, Farnesyl x receptor, FXR, HRR1, Farnesoid x activated receptor, Farnesoid X receptor, Farnesol receptor HRR-1, HRR-1, RXR-interacting protein 14, RIP14, Bile acid receptor, Farnesoid X nuclear receptor, Farnesoid X-activated receptor - Gene ID
- 9971
- NCBI Accession
- NP_005114
- UniProt
- Q96RI1
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Carbohydrate Metabolic Process
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