CA 19-9 antibody

Catalog No. ABIN336851

Product Details anti-CA 19-9 Antibody

Target: CA 19-9 (Gastrointestinal Cancer Antigen CA19-9 (CA 19-9))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CA 19-9 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody reacts with CA 19-9 antigen. Does not cross react with CA125, CA15-3, CEA. Epitope: Carbohydrate moiety.

Immunogen: Mucins from ovarian cyst

Clone: Sla203

Isotype: IgG1 kappa

Application Details

Application Notes: Immunohistochemistry (IHC) for formalin-fixed paraffin embedded (FFPE) tissue sections and frozen sections, the conc. antibodies can be diluted 1:50 -1:100 using polymer or streptavidin -biotin system for 30 mins at room temperature. The Prediluted antibodies are ready to use. The optimum dilution should be determined by the individual lab. Positive Control: Human colon, stomach, pancreas, intestine, breast carcinomas. Cellular Localization: Cytoplasmic.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The concentrated antibodies are supplied in PBS with 1% BSA, 0.05% azide, pH 7.4. The Prediluted antibody is supplied in our Universal antibody dilution buffer (AR-6526) green in color.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for CA 19-9

Target: CA 19-9 (Gastrointestinal Cancer Antigen CA19-9 (CA 19-9))

Alternative Name: CA 19-9 (CA 19-9 Products)

Background: The CA 19-9 antigen is a monosialosyl Le (a) blood group antigen which has been shown to be a useful-associated antigen for the diagnosis of gastrointestinal cancers. This antigen is known to be a ligand for the cell adhesion molecule called ELAM-1 (E-selectin, endothelial cell leukocyte adhesion molecule-1, which is present on cytokine-activated human endothelial cells. Selectin GMP-140 (CD62,PADGEM) binds to sialosyl Le (a) and sulfated glycans modulate this binding.