Synaptophysin antibody

Catalog No. ABIN336942

Product Details anti-Synaptophysin Antibody

Target: Synaptophysin (SYP)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Synaptophysin antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody reacts with Synaptophysin in neuroendocrine neoplasm of neural as well as epithelial type. Reference: Dottorini, ME etal. Cancer: 77: 1556-1565 (1996). Epitope: C-Terminus.

Immunogen: A synthetic peptide from C-terminus of human Synaptophysin

Application Details

Application Notes: Immunohistochemistry (IHC) for formalin-fixed paraffin embedded (FFPE) tissue sections and frozen sections. Dilute 1:100-1:200 using polymer or streptavidin -biotin system for 30 mins at room temperature. The Prediluted antibody is ready to be used. This antibody requires antigen retriever (boiling FFPE tissue sections in 10 mM citrate buffer, pH 6.0 for 10-20 mins. followed by cooling at room temp. for 20 mins). The optimum dilution should be determined by the individual lab. Positive Control: Human pancreas or GI tumor. Cellular Localization: Cytoplasmic.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Total immunoglobulin IgG purified by Protein A column in10 mM PO4, 150 mM NaCl, pH 7.4, 1% BSA, 0.05% sodium azide. Prediluted antibody is in our Universal antibody dilution buffer (green color). (Cat. # AR-6562) HostRabbit ReagentConc. Antibody, Predilut

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for Synaptophysin

Target: Synaptophysin (SYP)

Alternative Name: Synaptophysin (SYP Products)

Synonyms: syp-B antibody, xsypii antibody, MGC86267 antibody, MRXSYP antibody, A230093K24Rik antibody, AI848995 antibody, Syn antibody, p38 antibody, Syp1 antibody, mrxsyp antibody, syp antibody, xsypi antibody, synaptophysin S homeolog antibody, synaptophysin antibody, synaptophysin L homeolog antibody, synaptophysin a antibody, syp.S antibody, SYP antibody, syp antibody, Syp antibody, syp.L antibody, sypa antibody

Background: Synaptophysin is a synaptic vesicle glycoprotein with 4 transmembrane domain MW 38 kDa. This protein is present in neuroendocrine cells. It is also marker of endocrine tumors.

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity