ATG5 Autophagy Related 5 Homolog (S. Cerevisiae) (ATG5) (Extracellular Domain) antibody

Details for Product No. ABIN350087
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Antigen
Synonyms
ASP, APG5, APG5L, hAPG5, APG5-LIKE, Apg5l, Atg5l, Paddy, C88337, AW319544, 2010107M05Rik, 3110067M24Rik, apg5l, zgc:100934, ATATG5, ATG5, AUTOPHAGY 5, MKP11.20, MKP11_20, CG1643, DmAtg5, Dmel\\CG1643, ... show more
ASP, APG5, APG5L, hAPG5, APG5-LIKE, Apg5l, Atg5l, Paddy, C88337, AW319544, 2010107M05Rik, 3110067M24Rik, apg5l, zgc:100934, ATATG5, ATG5, AUTOPHAGY 5, MKP11.20, MKP11_20, CG1643, DmAtg5, Dmel\\CG1643, atg5 show less
Epitope
Extracellular Domain
(30), (11), (10), (10), (5), (4), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Human
(128), (75), (65), (31), (28), (14), (13), (13), (13), (12), (1), (1), (1), (1), (1)
Host
Rabbit
(92), (24), (12), (3), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(118), (56), (55), (19), (14), (10), (6), (4), (3), (2), (1)
Pubmed 5 references available
Catalog no. ABIN350087
Quantity 500 µg
Price
454.67 $   Plus shipping costs $45.00
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Immunogen A synthetic peptide from the extracellular domain of rat amiloride sensitive cation channel 2, neuronal (ACCN2, ASIC1) conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in mouse and shares 96% identity with hu
Specificity Specific for VN1R2.
Purification IgG
Alternative Name Autophagy protein 5 (ATG5, APG5)
Background ATG5 is an important element forautophagy and may also play an important role in the apoptotic process. Following conjugation to ATG12, the conjugate participates in the formation of autophagosome. While the mRNA is ubiquitously transcribed its expression is highly upregulated in apoptotic cells. Also known as: APG5-like, ATG5, ASP, APG5, APG5L, hAPG5, apoptosis-specific protein.
UniProt Q8NFZ6
Research Area Signaling
Application Notes Use at a concentration of 10-50 µg/mL.
The optimal concentration should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
Expiry Date 12 months
General Grand, Milner, Mustoe et al.: "A novel protein expressed in mammalian cells undergoing apoptosis." in: Experimental cell research, Vol. 218, Issue 2, pp. 439-51, 1995 (PubMed).

Hammond, Brunet, Johnson et al.: "Homology between a human apoptosis specific protein and the product of APG5, a gene involved in autophagy in yeast." in: FEBS letters, Vol. 425, Issue 3, pp. 391-5, 1998 (PubMed).

Mizushima, Sugita, Yoshimori et al.: "A new protein conjugation system in human. The counterpart of the yeast Apg12p conjugation system essential for autophagy." in: The Journal of biological chemistry, Vol. 273, Issue 51, pp. 33889-92, 1999 (PubMed).

Schmeiser, Armstrong, Hammond et al.: "Assignment of the yeast APG5 human homologue APG5L to chromosome band 6q21 by fluorescence in situ hybridisation." in: Cytogenetics and cell genetics, Vol. 87, Issue 3-4, pp. 213-4, 2000 (PubMed).

Simonsen, Birkeland, Gillooly et al.: "Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes." in: Journal of cell science, Vol. 117, Issue Pt 18, pp. 4239-51, 2004 (PubMed).

Hosts (92), (24), (12), (3), (3)
Reactivities (128), (75), (65), (31), (28), (14), (13), (13), (13), (12), (1), (1), (1), (1), (1)
Applications (118), (56), (55), (19), (14), (10), (6), (4), (3), (2), (1)
Conjugates (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (30), (11), (10), (10), (5), (4), (2), (2), (1), (1), (1), (1), (1)
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