C1q and Tumor Necrosis Factor Related Protein 5 (C1QTNF5) (Internal Region) antibody

Details for Product No. ABIN350268
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Antigen
Synonyms C1QTNF5, wu:fb02c10, wu:fb02f05, zgc:112378, CTRP5, Ctrp5
Epitope
Internal Region
(14), (12), (6), (5), (2), (1), (1), (1)
Reactivity
Human, Rat (Rattus), Mouse (Murine)
(54), (25), (17), (12), (12), (12)
Host
Rabbit
(50), (2), (1), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(45), (21), (11), (10), (8), (3), (2)
Pubmed 4 references available
Quantity 500 µg
Options
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Availability Will be delivered in 7 to 8 Business Days
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Catalog No. ABIN350268
454.67 $
Plus shipping costs $45.00

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Immunogen A synthetic peptide from internal region of human CTRP5 conjugated to an immunogenic carrier protein was used as the antigen. The antigen is homologous in rat and mouse.
Isotype IgG
Specificity Specific for CTRP5.
Alternative Name CTRP5
Background Defects in C1QTNF5 are a cause of late-onset retinal degeneration (LORD). LORD is an autosomal dominant disorder characterized by onset in the fifth to sixth decade with night blindness and punctate yellow-white deposits in the retinal fundus, progressing to severe central and peripheral degeneration, with choroidal neovascularization and chorioretinal atrophy.
Subcellular location: Secreted Also known as: Complement C1q tumor necrosis factor-related protein 5, C1QTNF5.
Research Area Neurology, Innate Immunity, Cytokines
Application Notes A concentration of 10-50 µg/ml is recommended.
The optimal concentration should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
General Hayward, Shu, Cideciyan et al.: "Mutation in a short-chain collagen gene, CTRP5, results in extracellular deposit formation in late-onset retinal degeneration: a genetic model for age-related macular degeneration." in: Human molecular genetics, Vol. 12, Issue 20, pp. 2657-67, 2003 (PubMed).

Clark, Gurney, Abaya et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, 2003 (PubMed).

Zhang, Henzel: "Signal peptide prediction based on analysis of experimentally verified cleavage sites." in: Protein science : a publication of the Protein Society, Vol. 13, Issue 10, pp. 2819-24, 2004 (PubMed).

Taylor, Noguchi, Totoki et al.: "Human chromosome 11 DNA sequence and analysis including novel gene identification." in: Nature, Vol. 440, Issue 7083, pp. 497-500, 2006 (PubMed).

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