Search, Find and Buy Antibodies, ELISA Kits and Proteins.
Loading Loading
Order hotline:
phone +1 404 474 4654
fax +1 888 205 9894 (TF)
Details for Product No. ABIN350518

Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (2nd Cytoplasmic Domain) antibody

Request
Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms GluN2A, NMDAR2A, NR2A, EPND, GRIN2A, nr2a
Epitope
»Alternatives 2nd Cytoplasmic Domain
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN350518
Quantity 500 µg
Price
454.67 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from the 2d cytoplasmic domain of human NMDAR2A (GRIN2A) conjugated to an immunogenic carrier protein was used as the immunogen.
Isotype IgG
Specificity Appears to be specific for NMDAR2A.
Purification The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide is removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Purity IgG
Alternative Name NMDAR2A (GRIN2A)
Background Function: NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Activation requires binding of agonist to both types of subunits.
Subcellular location: Cell membrane, Multi-pass membrane protein. Cell junction › synapse › postsynaptic cell membrane, Multi-pass membrane protein. Also known as: GRIN2A, Glutamate receptor subunit epsilon-1, Glutamate [NMDA] receptor subunit epsilon-1, N-methyl D-aspartate receptor subtype 2A, NMDE1, NR2A.
UniProt Q12879
Application Notes IHC, WB. A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Foldes, Adams, Fantaske et al.: "Human N-methyl-D-aspartate receptor modulatory subunit hNR2A: cloning and sequencing of the cDNA and primary structure of the protein." in: Biochimica et biophysica acta, Vol. 1223, Issue 1, pp. 155-9, 1994 (PubMed).

Hess, Daggett, Crona et al.: "Cloning and functional characterization of human heteromeric N-methyl-D-aspartate receptors." in: The Journal of pharmacology and experimental therapeutics, Vol. 278, Issue 2, pp. 808-16, 1996 (PubMed).

Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Munton, Tweedie-Cullen, Livingstone-Zatchej et al.: "Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 2, pp. 283-93, 2007 (PubMed).

Molina, Horn, Tang et al.: "Global proteomic profiling of phosphopeptides using electron transfer dissociation tandem mass spectrometry." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 7, pp. 2199-204, 2007 (PubMed).

Alternatives for antigen "Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A)", type "Antibodies"
Hosts (95), (5), (2)
Reactivities (83), (50), (49), (46), (32), (31), (30), (1)
Applications (59), (34), (30), (21), (20), (20), (8), (4), (3), (3), (2), (1)
Conjugates (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2)
Epitopes (20), (19), (13), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Beacon