Vesicle Docking Protein (VDP, USO1, TAP, Transcytosis Associated Protein) (Internal Region) antibody

Details for Product No. ABIN351344
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Antigen
Epitope
Internal Region
(3)
Reactivity
Mouse (Murine), Rat (Rattus), Human
(3), (3), (2)
Host
Rabbit
(3)
Clonality
Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(3), (3)
Pubmed 3 references available
Catalog no. ABIN351344
Quantity 500 µg
Price
454.67 $   Plus shipping costs $45.00
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Immunogen A synthetic peptide from the internal part of human Vesicle-docking protein (VDP, USO1, TAP, Transcytosis-associated protein) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in rat and moue.
Specificity Specific for KCNK13.
Purification IgG
Background Function: General vesicular transport factor required for intercisternal transport in the Golgi stack, it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity.
Subcellular location: Cytoplasm, cytosol. Golgi apparatus membrane, Peripheral membrane protein. Note: Recycles between the cytosol and the Golgi apparatus during interphase. Also known as: Protein USO1 homolog, Transcytosis-associated protein, TAP, General vesicular transport factor p115, USO1, VDP.
UniProt Q9HB14
Research Area Signaling, Metabolism
Application Notes A concentration of 10-50 µg/mL is recommended.
The optimal concentration should be determined by the end user.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
Expiry Date 12 months
General Sohda, Misumi, Yano et al.: "Phosphorylation of the vesicle docking protein p115 regulates its association with the Golgi membrane." in: The Journal of biological chemistry, Vol. 273, Issue 9, pp. 5385-8, 1998 (PubMed).

Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Han, Ye, Zhou et al.: "Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography." in: Proteomics, Vol. 8, Issue 7, pp. 1346-61, 2008 (PubMed).

Hosts (3)
Reactivities (3), (3), (2)
Applications (3), (3)
Epitopes (3)
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