Solute Carrier Family 17 (Sodium-Dependent Inorganic Phosphate Cotransporter), Member 7 (SLC17A7) (AA 500-560) antibody

Details for Product No. ABIN351379
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Antigen
Synonyms vglut1, vglut2, slc17a7, MGC146483, SLC17A7, 2900052E22Rik, AI851913, Vglut1, BNPI, VGLUT1, slc17a6
Epitope
AA 500-560
(27), (18), (4), (2), (2), (2), (2), (1)
Reactivity
Human, Rat (Rattus), Mouse (Murine)
(55), (32), (26), (18), (18), (17), (17), (2)
Host
Rabbit
(31), (22), (4), (4), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB), Flow Cytometry (FACS)
(44), (31), (22), (14), (10), (9), (8), (5), (3), (2), (2), (1)
Pubmed 5 references available
Quantity 500 µg
Options
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Catalog No. ABIN351379
454.67 $
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Immunogen A synthetic peptide from aa region 500-560 of rat VGluT1 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in human and mouse.
Isotype IgG
Specificity Specific for VGLUT1 (both isoforms 1 and 2).
Alternative Name VGluT1
Background Function: Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate.
Subcellular location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Membrane, Multi-pass membrane protein. Cell junction, synapse, synaptosome. Also known as: Vesicular glutamate transporter 1, VGlU1, Solute carrier family 17 member 7, Brain-specific Na(+)-dependent inorganic phosphate cotransporter, Bnpi.
Application Notes A concentration of 10-50 µg/ml is recommended.
The optimal concentration should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
General Ni, Rosteck, Nadi et al.: "Cloning and expression of a cDNA encoding a brain-specific Na(+)-dependent inorganic phosphate cotransporter." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 12, pp. 5607-11, 1994 (PubMed).

Takamori, Rhee, Rosenmund et al.: "Identification of a vesicular glutamate transporter that defines a glutamatergic phenotype in neurons." in: Nature, Vol. 407, Issue 6801, pp. 189-94, 2000 (PubMed).

Herzog, Bellenchi, Gras et al.: "The existence of a second vesicular glutamate transporter specifies subpopulations of glutamatergic neurons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 21, Issue 22, pp. RC181, 2001 (PubMed).

Takamori, Rhee, Rosenmund et al.: "Identification of differentiation-associated brain-specific phosphate transporter as a second vesicular glutamate transporter (VGLUT2)." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 21, Issue 22, pp. RC182, 2001 (PubMed).

Nogami, Ogasawara, Mimura et al.: "Developmentally-regulated expression of tissue-specific splice variant of rat vesicular glutamate transporter 1 in retina and pineal gland." in: Journal of neurochemistry, Vol. 99, Issue 1, pp. 142-53, 2006 (PubMed).

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