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Actin, alpha 2, Smooth Muscle, Aorta (ACTA2) antibody
| Antigen | Actin, alpha 2, Smooth Muscle, Aorta (ACTA2) |
| Synonyms |
AAT6, ACTSA, Actvs, a-SMA, SMalphaA, 0610041G09Rik, wu:fb63d03, MGC78870, ACTA2, actc1, actsa, MGC89192, MGC127800, ACT-4, DKFZp469E0314, Acta2, asma, acta, cftd, mpfd, nem1, nem2, nem3, acta2, cftd1, ...
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| Clonality | Monoclonal (1A4) |
| Host |
 Alternatives Mouse |
| Reactivity |
Alternatives Cow (Bovine) |
| Application |
Alternatives Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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| Catalog no. | ABIN356281 |
| Quantity | 0.1 mg (0.2 mg/ml) (Variants) |
| Price | 195.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 7 to 10 Business Days |
Additional Information
| Characteristics | Synonyms: Alpha-actin-2, ACTVS, GIG46, Cell growth-inhibiting gene 46 protein |
| Alternative name | Aortic smooth muscle Actin / ACTA2 |
| Swiss-Prot | P62736 |
| Immunogen | N-terminal decapeptide of alpha smooth muscle isoform of actin, acetylated at theN-terminus. Remarks: Epitope: Acetyl group with N- terminal four amino acids of peptide chain of alphasmooth muscle. |
| Cross-Reactivity | Cow (Bovine), Chicken, Human, Mouse (Murine), Rabbit, Rat (Rattus) |
| Isotype | IgG2a (Matching secondary antibodies) |
| Clone | 1A4 |
| Description | Actin is a globular, roughly 42-kDa protein found in all eukaryotic cells. Actin participatesin many important cellular functions, including muscle contraction cell motility celldivision and cytokinesis vesicle and organelle movement, cell signaling, and theestablishment and maintenance of cell junctions and cell shape. Expression of smoothmuscle alpha actin is regulated by hormones and cell proliferation and is altered bypathological conditions including onogenic transformation and atherosclerosis. |
| Specificity | This antibody recognises ACTIN alpha Smooth Muscle. Cellular Localization: Cytoplasmic. Species: Human, Baboon, Bovine, Rabbit, Rat, Mouse and Chicken. Others not tested. |
| Synonyms | AAT6, ACTSA, Actvs, a-SMA, SMalphaA, 0610041G09Rik, wu:fb63d03, MGC78870, ACTA2, actc1, actsa, MGC89192, MGC127800, ACT-4, DKFZp469E0314, Acta2, asma, acta, cftd, mpfd, nem1, nem2, nem3, acta2, cftd1, cftdm, MGC52636, MGC79039 |
Application Details
| Application Notes | Suitable for Immunohistochemistry and Immunocytochemistry (Frozen or Formalin-FixedParaffin-Embedded (FFPE) tissue sections and cell smears)For IHC dilute concentared antibody at 1/50-1/100, use streptavidin~biotin system orpolymer system, incubate 30 minutes at room temperature. Recommended Positive Control: Human uterus, gastrointestinal tissue, Leiomyosarcoma. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. |
| Concentration | 0.2 mg/ml |
| Purification | Purified |
| Buffer | PBS, pH 7.4 containing 1% BSA as stabilizer and 0.05% Sodium Azide aspreservative. |
| Storage | Storethe antibody undiluted at 2-8Cfor one month or (in aliquots) at -20Cfor longer. Avoid repeated freezing and thawing. Shelf life: One year from despatch. |
| Research Area | Extracellular Matrix, Cell/Tissue Markers |
| Restrictions | For Research Use only |
Alternatives
Alternatives for antigen "Actin, alpha 2, Smooth Muscle, Aorta (ACTA2)", type "Antibodies"
| Hosts | Mouse (33), Rabbit (11), Goat (4) |
| Reactivities | Human (35), Rat (Rattus) (17), Chicken (16), Mouse (Murine) (16), Cow (Bovine) (14), Rabbit (13), Baboon (3), Dog (Canine) (2), Monkey (2), Vertebrates (2) |
| Applications | Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (39), Western Blotting (WB) (18), Immunofluorescence (IF) (14), Immunohistochemistry (Frozen Sections) (IHC (fro)) (10), Enzyme Immunoassay (EIA) (7), Immunohistochemistry (IHC) (6), ELISA (5), ELISA (Detection) (1), Flow Cytometry (FACS) (1), Immunoprecipitation (IP) (1) |
| Epitopes | N-Term (5), Ab-1 (2) |
