ADAMTS1
Reactivity: Rat
WB, IHC, IF/ICC, IP
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Immunohistochemistry on Paraffin Embedded Tissues: 20 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
1.0 mg/mL
Buffer
PBS containing 0.09 % Sodium Azide as preservative.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target
ADAMTS1
(ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 1 (ADAMTS1))
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Background
ADAMTS1 is a metalloproteinase of the ADAM (A Disintegrin And Metalloproteinase) family containing disintegrin-like domains. ADAMTS1, also known as METH1, was first described as a protein elevated in invasive mouse tumors. Initial findings indicated a role for ADAMTS1 in tumor progression, since the protein was preferentially expressed in more invasive tumor cell lines. ADAMTS1 is necessary for normal growth, fertility, and organ morphology and function.Synonyms: A disintegrin and metalloproteinase with thrombospondin motifs 1, ADAM-TS1, ADAMTS-1, KIAA1346