Did you know that you can buy products from over 140 different suppliers from us?

Lemur tyrosine Kinase 2 (LMTK2) (N-Term) antibody

Details for Product No. ABIN359287
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms AATYK2, BREK, KPI-2, KPI2, LMR2, cprk, 2900041G10Rik, A330101P12Rik, aatyk2
Epitope
N-Term
(10), (7), (5), (1), (1), (1), (1)
Reactivity
Human
(39), (1), (1), (1)
Host
Rabbit
(28), (7), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(35), (32), (17), (10), (9), (4), (2), (1)
Pubmed 5 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Catalog No. ABIN359287
357.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human LMTK2.
Specificity This antibody reacts to LMTK2.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Alternative Name LMTK2
Background Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).
Alternate names: AATYK2, Apoptosis-associated tyrosine kinase 2, BREK, Brain-enriched kinase, CDK5/p35-regulated kinase, CPRK, EC=2.7.11.1, KIAA1079, KPI2, Kinase/phosphatase/inhibitor 2, LMR2, LMTK2, Lemur tyrosine kinase 2, Serine/threonine protein kinase KPI-2, Serine/threonine-protein kinase LMTK2
Gene ID 22853
NCBI Accession 9606
UniProt Q8IWU2
Application Notes ELISA: 1/1,000. Immunohistochemistry: 1/50 - 1/100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
Expiry Date 12 months
Background publications Wang, Brautigan: "A novel transmembrane Ser/Thr kinase complexes with protein phosphatase-1 and inhibitor-2." in: The Journal of biological chemistry, Vol. 277, Issue 51, pp. 49605-12, 2002 (PubMed).

Scherer, Cheung, MacDonald et al.: "Human chromosome 7: DNA sequence and biology." in: Science (New York, N.Y.), Vol. 300, Issue 5620, pp. 767-72, 2003 (PubMed).

Kesavapany, Lau, Ackerley et al.: "Identification of a novel, membrane-associated neuronal kinase, cyclin-dependent kinase 5/p35-regulated kinase." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 23, Issue 12, pp. 4975-83, 2003 (PubMed).

Hillier, Fulton, Fulton et al.: "The DNA sequence of human chromosome 7." in: Nature, Vol. 424, Issue 6945, pp. 157-64, 2003 (PubMed).

Kawa, Fujimoto, Tezuka et al.: "Involvement of BREK, a serine/threonine kinase enriched in brain, in NGF signalling." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 9, Issue 3, pp. 219-32, 2004 (PubMed).

Hosts (28), (7), (3)
Reactivities (39), (1), (1), (1)
Applications (35), (32), (17), (10), (9), (4), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1)
Epitopes (10), (7), (5), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN359287
357.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
back to top