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RPTOR Independent Companion of MTOR, Complex 2 (RICTOR) (N-Term) antibody

Details for Product No. ABIN359480
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Antigen
Synonyms AVO3, AW492497, 4921505C17Rik, 6030405M08Rik, D530039E11Rik, PIA, mAVO3, Fyb
Epitope
N-Term
(21), (12), (10), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Reactivity
Human
(97), (47), (28), (25), (24), (24), (14), (13)
Host
Rabbit
(67), (25), (8)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(64), (49), (26), (20), (19), (18), (9), (8), (6), (2), (2), (1), (1), (1)
Pubmed 3 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Catalog No. ABIN359480
357.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human RICTOR.
Specificity This antibody detects RICTOR at N-term.
Purification Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name RICTOR
Background RICTOR and MTOR (FRAP1) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth.
Alternate names: KIAA1999, Rapamycin-insensitive companion of mTOR, mAVO3
Molecular Weight 192087 Da
Gene ID 253260
NCBI Accession 9606
UniProt Q6R327
Research Area Signaling
Application Notes ELISA 1: 1,000. Western blot 1: 50 - 1: 100. Immunohistochemsitry 1: 10 - 1: 50. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
Expiry Date 12 months
Background publications Jacinto, Facchinetti, Liu et al.: "SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity." in: Cell, Vol. 127, Issue 1, pp. 125-37, 2006 (PubMed).

Yang, Inoki, Ikenoue et al.: "Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity." in: Genes & development, Vol. 20, Issue 20, pp. 2820-32, 2006 (PubMed).

Pearce, Huang, Boudeau et al.: "Identification of Protor as a novel Rictor-binding component of mTOR complex-2." in: The Biochemical journal, Vol. 405, Issue 3, pp. 513-22, 2007 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN359480
357.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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