MAP3K10 antibody (C-Term)

Catalog No. ABIN360309

The Rabbit Polyclonal anti-MAP3K10 antibody (ABIN360309) specifically detects MAP3K10 in WB, IHC (p) and EIA. The antibody is reactive with Human samples.

Quick Overview for MAP3K10 antibody (C-Term) (ABIN360309)

Target: MAP3K10 (Mitogen-Activated Protein Kinase Kinase Kinase 10 (MAP3K10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP3K10 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-MAP3K10 Antibody

Binding Specificity: C-Term

Specificity: This antibody reacts to MLK2.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human MLK2.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for MAP3K10

Target: MAP3K10 (Mitogen-Activated Protein Kinase Kinase Kinase 10 (MAP3K10))

Alternative Name: MAP3K10

Background: MLK2 is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can bephoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.Synonyms: MLK2, MST, Mitogen-activated protein kinase kinase kinase 10, Mixed lineage kinase 2, Protein kinase MST

Gene ID: 4294, 9606

UniProt: Q02779