Protein Kinase C and Casein Kinase Substrate in Neurons 3 (PACSIN3) (N-Term) antibody

Details for Product No. ABIN360557, Supplier: Log in to see
Antigen
  • Pacsin1
  • wu:fa11d03
  • wu:fj67e09
  • wu:fq16a06
  • zgc:56324
  • MGC82145
  • PACSIN3
  • sdpiii
  • SDPIII
  • 4921507A02Rik
  • 6330413E15Rik
  • AW413130
  • SdpIII
  • protein kinase C and casein kinase substrate in neurons 3
  • pacsin3
  • PACSIN3
  • Pacsin3
Epitope
N-Term
32
3
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
98
38
37
15
14
3
3
3
2
2
1
1
1
Host
Rabbit
51
33
16
Clonality
Polyclonal
Conjugate
Un-conjugated
4
4
4
3
3
3
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
82
33
32
26
13
11
3
3
2
Options
Supplier
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Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PACSIN3.
Isotype Ig
Specificity This antibody reacts to PACSIN3.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Alternative Name PACSIN3 (PACSIN3 Antibody Abstract)
Background Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.Synonyms: Endophilin I, Protein kinase C and casein kinase substrate in neurons protein 3, SH3 domain-containing protein 6511
Gene ID 29763, 9606
UniProt Q9UKS6
Research Area Signaling
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Supplier Images
 image for anti-Protein Kinase C and Casein Kinase Substrate in Neurons 3 (PACSIN3) (N-Term) antibody (ABIN360557) anti-Protein Kinase C and Casein Kinase Substrate in Neurons 3 (PACSIN3) (N-Term) antibody
 image for anti-Protein Kinase C and Casein Kinase Substrate in Neurons 3 (PACSIN3) (N-Term) antibody (ABIN360557) anti-Protein Kinase C and Casein Kinase Substrate in Neurons 3 (PACSIN3) (N-Term) antibody (Image 2)
Background publications Howard, Nelson, Maciewicz, Blobel: "Interaction of the metalloprotease disintegrins MDC9 and MDC15 with two SH3 domain-containing proteins, endophilin I and SH3PX1." in: The Journal of biological chemistry, Vol. 274, Issue 44, pp. 31693-9, 1999 (PubMed).

Oohata, Takeuchi: "Separation and biochemical characterization of the two cell types present in the pseudoplasmodium of Dictyostelium mucoroides." in: Journal of cell science, Vol. 24, pp. 1-9, 1977 (PubMed).

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